CBD

[Mize]

Doesn't work at all for me. Regular cannabis doesn't really either, unless you count caring less about the pain effective "pain management". Shortly after using, my pain levels actually spike, until I zone out, and stop caring. Still hurts though.

Well there's a couple things here. One, distraction from pain is absolutely pain management. If it makes you fuzzy headed that's not exactly worse than taking opioids which muddle the mind while creating addiction. So regular old weed is like being able to tune out the screaming child on the plane directly behind you. If you stop and try to notice the kid, he's screaming just as loud as before, but you can tune it out.

Two, CBD from hemp is not terribly useful. There's at least one study that showed CBD to be much more effective when it was derived from the (female) cannabis sativa strain that was hybridized to produce nearly zero THC and lots of CBD as compared to CBD from the male, hemp plant. I'll find a link, hang on.

Ah, here is a summary of it: https://www.projectcbd.org/science/c...hole-plant-cbd

I've read the actual paper and I've not read that link yet, but essentially the hemp-derived stuff has a effect that responds with a bell-curve from dosage; i.e. it starts to have an effect but with increasing dose it stops working. The female plant, with all the rest of the cannabis compounds has an increasing effect with dosage.

The real problem is standardization. While I was in CA recently I used a 1:1 THC:CBD vape oil pen that did wonders on my nerve pain with minimal buzz, but a second "1:1" vape pen had a much more subdued effect.

I also bought a 100% cannabis sativa CBD pen that was interesting because there was no head effect at all, but after an hour or so I'd realize I hadn't been experiencing the nerve pain at the higher level - i.e. it worked but the lack of the fuzziness made its effect less noticeable which is net good.

[Mize]

Stumbled on this today too: https://www.ncbi.nlm.nih.gov/pubmed/21310467

Lots of terminology I'm unfamiliar with, but it would appear that there is some evidence CBD could help with bladder spasms.
Sure wish Ohio would get their spit together so I could give that an whirl.

I'm waiting on a pre-auth for botox now since the funking oxybutynin is now less effective and more problematic (talk about fuzzy head!)

[annev308]

The real problem is standardization. While I was in CA recently I used a 1:1 THC:CBD vape oil pen that did wonders on my nerve pain with minimal buzz, but a second "1:1" vape pen had a much more subdued effect.

I also bought a 100% cannabis sativa CBD pen that was interesting because there was no head effect at all, but after an hour or so I'd realize I hadn't been experiencing the nerve pain at the higher level - i.e. it worked but the lack of the fuzziness made its effect less noticeable which is net good.

Yeah, this - the standardization. Or at least the provision of enough information that folks can standardize their own usage successfully. The dispensary I go to does gas chromatography on batches of product, so it’s possible to figure out not only how much CBD you’re getting but also look at the other terpene ratios and over time sort out what works best that way for me. I have tried various topical CBD products - when they’re effective they’re great, but often they’re inconsistent within brand and even batch. A good dispensary can really make a difference.

[Mize]

That reminds me, I picked up a THC:CBD = 1 salve in CA as well and it works wonders on dysesthesia with zero psychoactive component. Previously I used a compound cream with ketamine, baclofen and more that helped but had a wicked rebound.

[royb]

buylegalmeds.com has some awesome products they are a great company! I use the 850mg dabs and the cbd flower. I have tried cbd products from a lot of other companys and it had no effect.

[NorthQuad]

Once legal, doctors, researchers, scientists will finally be able to collaborate and run trials to find effective doses. Until then it'll be left up to individuals to experiment. I'd advise for anyone not familiar with cannabis (and where it's legal) that you find a reputable source. Avoid anything not grown in a licenced grower under proper lab conditions. Otherwise who knows what you could be buying.

I haven't yet tried using CBD but definitely will be once fully legal in Canada and various brands that I'm interested in hit the market. I look forward to it.

[Oddity]

That reminds me, I picked up a THC:CBD = 1 salve in CA as well and it works wonders on dysesthesia with zero psychoactive component. Previously I used a compound cream with ketamine, baclofen and more that helped but had a wicked rebound.

What did they do to make THC non-psychoactive?! Seems strange...unless it was such a small dose, or you're a chronic from way back!

[NorthQuad]

What did they do to make THC non-psychoactive?! Seems strange...unless it was such a small dose, or you're a chronic from way back!

I know there are different strains of cannabis plant. And processes to extract. So to have a controlled small amount in a single dose is enough alone to avoid the psychoactive effects.

[Mize]

What did they do to make THC non-psychoactive?! Seems strange...unless it was such a small dose, or you're a chronic from way back!

It's a topical balm/salve labeled "non-psychoactive" and it certainly hasn't been for me. I don't know how much THC it takes to get high with a transdermal entry point. I suppose if I tried to vape it or eat it, but then it has other ingredients like bees wax and coconut oil...probably not good to get those in one's lungs.

[Moongazr]

buylegalmeds.com has some awesome products they are a great company! I use the 850mg dabs and the cbd flower. I have tried cbd products from a lot of other companys and it had no effect.

Have you used any of the coupon codes? I've tried a few but it comes back as not valid in my country. (USA) ???

[SCI-Nurse]

What did they do to make THC non-psychoactive?! Seems strange...unless it was such a small dose, or you're a chronic from way back!

THC and CBD are two separate chemicals that occur in marijuana. CBD is not "made" from THC.

Marijuana contains at least 80 chemicals called cannabinoids. Researchers are evaluating how effective some of these cannabinoids might be in controlling symptoms of certain medical conditions. For example:

• THC. An abbreviation for delta-9-tetrahydrocannabinol, THC is the main component responsible for marijuana's mind-altering effect. It also may help treat signs and symptoms such as nausea and vomiting that are associated with a number of medical conditions.
• Cannabinol and cannabidiol. These compounds have some of the properties of THC, but cause less psychoactive effects — the high.

Here is some further information: https://medicalmarijuana.procon.org/...stionID=000636

(KLD)

[Oddity]

THC and CBD are two separate chemicals that occur in marijuana. CBD is not "made" from THC.

Marijuana contains at least 80 chemicals called cannabinoids. Researchers are evaluating how effective some of these cannabinoids might be in controlling symptoms of certain medical conditions. For example:

• THC. An abbreviation for delta-9-tetrahydrocannabinol, THC is the main component responsible for marijuana's mind-altering effect. It also may help treat signs and symptoms such as nausea and vomiting that are associated with a number of medical conditions.
• Cannabinol and cannabidiol. These compounds have some of the properties of THC, but cause less psychoactive effects ? the high.

Here is some further information: https://medicalmarijuana.procon.org/...stionID=000636

(KLD)

All common knowledge. I was questioning how something that includes a 1:1 relationship of CBD to THC could be "non-psychoactive", as Mize posted was the case.

[Mize]

Might want to look up how much typical THC gets to the blood system. The ketamine didn't seem to.

[lynnifer]

Was just discussing CBD in oral form with some former co-workers in law enforcement. 2ng/mL will be a warning and 5ng/mL will be impaired.

I've read that 2ng/mL (2 nanograms per millilitre of blood) would require a person to stop smoking/ingesting etc for 5-7 days before driving.

Useless. I have trouble, especially at night with sleep and pain and was hoping an oral dosage of CBD would help.

[Mize]

Might want to look up how much topical THC gets to the blood system.
The ketamine didn't seem to and I'd be more worried about the rave drug over weed.