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ppar alpha and gamma agonist

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  • ppar alpha and gamma agonist

    According to these research papers from Pubmed:

    ppar alpha agonist can rapidly reduce chronic pain
    and ppar gamma agonists also help with pain.

    The research I guess uses experimental drugs.

    It occurred to me that, if we can find safe natural compounds that have ppar alpha agonist actions and ppar gamma agonist actions, we might have a pain control nutrient on our hands.

    Bodybuilders use sesamin oil if I'm not wrong and I think its a ppar alpha agonist. Could it work?
    Does ppar alpha have subtypes?

    Is there a natural ppar gamma agonist out there.
    Anyone care to join in the discussion?