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    Ketamine

    Having run out of pain management options I just started a ketamine program.

    My wife is worried I'll go bonkers on it and go postal

    Doc laughed and said with the minimal start up dosage we'll not be surprised by any weird behavior caused from a large dose.

    Has anyone here tried it?

    My doc only has a couple patients who responded well but they were hard core long term pain patients who have really come back to a more normal life.

    besides the gorilla sitting next to me said he'd help me out if i went nuts


    Bill
    Kindly,

    The Ketamine Kitty

    All the tears, all the pain, all the rage through the night (apolgies to the rewrite) RR

    Next time I die make sure I'm gone,
    don't leave 'em nothing to work on JT

    And I ain't nothin but a dream JM

    #2
    Hey Bill.
    I don't know anything about ketamine program. What are the goals of the treatment? Is it just for 5 days? Or long term?
    I just perused this review article about Ketamine for chronic pain written in 2003. I thought people might look at this.
    http://www.anesthesia-analgesia.org/.../97/6/1730.pdf

    Dejerine - this review says that they have tried this for intractable Central Pain. What is your take on this?

    thanks,
    arndog

    Comment


      #3
      But first for the important question - What's the gorilla's name?

      Seriously, I really REALLY hope this helps.

      Here's an article on ketamine - but not sure if you're doing infusinos, oral, or gel

      http://www.rsdfoundation.org/en/Ketamine_Treatment.html

      Comment


        #4
        Nasal spray 4x a day. A bit irritating to the nose and tastes funky. No noticeable effects yet, good or bad.

        Bill
        Kindly,

        The Ketamine Kitty

        All the tears, all the pain, all the rage through the night (apolgies to the rewrite) RR

        Next time I die make sure I'm gone,
        don't leave 'em nothing to work on JT

        And I ain't nothin but a dream JM

        Comment


          #5
          Interesting, I hadn't heard of that. I really hope this goes well for you Bill.

          I'm interested for my husband as well, might be something he'd try. Although I told him I wasn't particularly thrilled with the prospect of a giant version of the "ketamine kitty" (we were joking).

          Ketamine is used often as a veterinary anesthetic, in combination with valium. The problem with kittys is that if the valium wears off before the ketamine does (oops) you have a hallucinating wild kitty complete with claws and fangs - not so fun for the vet, or the poor tech who has to catch the thing.

          Please don't view that as anything to worry about though, it was just intended as mildly funny - anesthetic doses are VERY different, and I don't remotely mean anything similar would happen to a human.

          Comment


            #6
            Ketamine Kitty

            TAM LOL !

            I do know a fair amount about ketamine, researched it first and am on such a low "start and see" dose there is virtually no chance I'd go KK.

            My wife also researches everything for herself and it made her nervous. I have my Samurai Sword collection out for routine maintenence and she was worried I'd go Samurai. Doc assured her not to worry.

            Can't say it has helped but the dose is too small. Next week I satrt to titrate up and then we'll see what it can do. Will post about it.

            bill
            Kindly,

            The Ketamine Kitty

            All the tears, all the pain, all the rage through the night (apolgies to the rewrite) RR

            Next time I die make sure I'm gone,
            don't leave 'em nothing to work on JT

            And I ain't nothin but a dream JM

            Comment


              #7
              I figured you probably had, but didn't want anyone else who read it to be concerned.

              LOL re. the sword collection - this sounds like an exercise in "How many ways can we make Bill's wife twitch?"

              And now we have a new acronym - KK (only two of them lol)

              I'll be crossing my fingers and hoping for some good reports from you before too long.

              Comment


                #8
                After your story about tearing into the guy who parked in the handicap parking without a placard, I too was worried about you, Bill, going postal on Ketamine. Didn't want you to enter the 'K. Hole'.
                My fingers are crossed also that upping the dose will help you.

                Comment


                  #9
                  Wow, I didn't know Ketamine was used for chronic pain... I'll have to do a little research on it. I hope it works for you Bollefen!
                  Donate for Clinical Trials at: http://www.justadollarplease.org/

                  Information on U.S. Clinical Trials at: http://www.scinetusa.org/

                  Comment


                    #10
                    Good luck Bill. I know you hurt badly.
                    Last edited by quad79; 20 Nov 2009, 10:24 AM.

                    Comment


                      #11
                      I believe I must respectfully disagree with some of that.

                      Patients who take medication for pain very rarely become addicted. Physically dependant, sure, but not addicted. People stealing it for a high - they can get addicted. Not generally pain patients.

                      I am pretty sure Ketamine is widely used in veterinary anesthesia.

                      From the Veterinary Anesthesia & Analgesia Support Group website:

                      "NMDA ANTAGONISTS helps to prevent sensitization of the central nervous system, reducing the exaggerated pain response that is otherwise a potential development after any significant traumatic or surgical event[x]. NMDA antagonists enhance opioid analgesia and they help to combat the opioid tolerance that may occur when opioids are given for long periods of time.
                      KETAMINE is the most commonly utilized veterinary NMDA antagonist.

                      Your reference to American Veterinarian Association - I presume you mean the AVMA (American Veterinary Medical Association) - I would be very interested to see if they have some recommendation about Ketamine - I couldn't find it - do you have a link?

                      There is recent research into using ketamine for pain control in humans. Some patients have been helped (even made pain-free) from ketamine comas. For example, Dr. Lubenow at Rush in Chicago is doing some work using ketamine (infusions I believe).

                      I don't mean to say everyone should rush out and get ketamine, of course. But it does seem to have some promise in pain management, especially for difficult cases.

                      Comment


                        #12
                        No link Tam, I just know.

                        Comment


                          #13
                          I just asked a veterinarian, who said it's still widely used, and he believes there is no AVMA statement against it that we're aware of. It's possible there is something, and I haven't found it.

                          Just for interest, here is the link from my prior quote (sorry, I had forgotten before):

                          http://www.vasg.org/ (veterinary anesthesia and alagesia support)

                          Although it is veterinary, that site has a rather good write-up about pain (which is really no different in animals than in humans)

                          Merck veterinary manual also says:

                          http://www.merckvetmanual.com/mvm/in...&word=ketamine

                          "Ketamine has long been known to provide excellent superficial analgesia but rather poor visceral analgesia. Recently, interest in ketamine has increased because of its potential role in preventing wind-up (sensitization) of central nociceptive pathways. Ketamine is an antagonist of the excitatory neurotransmitter glutamate at the N-methyl-D-aspartate (NMDA) receptors in the spinal cord and brain. Inhibition of the NMDA receptors prevents or decreases exaggerated pain states in laboratory animals and people. Thus, ketamine may be incorporated into the anesthetic protocol to prevent the development of exaggerated or chronic pain states. "

                          Hope Bill doesn't mind this digression, but my point is that Ketamine is getting increased interest, both in animal and human pain research, due to its effect on NMDA receptors.

                          Of course, the animals at times get things before the humans do, so it is often interesting to see what comes up in the veterinary world.

                          Comment


                            #14
                            i was given ketamine during a surgical procedure. upon awaking i was freaking out and was so panicky. i had a very hard time with this drug. it states that anxiety is a side effect from this drug. everyone acts differently to medications.. hopefully this wont be the case for you. plus i was told is a very old drug thats not used much for anesthesia any more. i dont know about pain management.

                            Comment


                              #15
                              Tam, I'm not going to debate it because I have no written facts to paste & give you. I've just worked the field & have discussions with others still in it. I still have to disagree though that those with chronic pain can't become addicted. It's very easy especially with this drug because it can be so calming.

                              duj,yes it can cause major anxiety & restlessness when wearing off. This is where I've seen the abuse take place(in a friend I worked with), she kept needing her fixes to then calm the anxiety caused by the rapid heartbeat down. It can be a viscious cycle. You should see the animals coming off of it, it's surprising they don't hurt themselves from freaking out so badly.

                              Comment

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