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Vitamin D reverses diabetic neuropathy

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  • Vitamin D reverses diabetic neuropathy

    Vitamin D reverses diabetic neuropathy

    by Dr Linda Calabresi
    15 April 2008

    Vitamin D supplementation is an effective treatment of neuropathic pain in Type 2 diabetes patients, new Australian research suggests.

    Previous research has found that vitamin D deficiency is common in patients with Type 2 diabetes, but its effect on neuropathic pain has not previously been tested, say study authors Drs Paul Lee and Roger Chen from Concord Repatriation General Hospital.

    Their study, published in today’s Archives of Internal Medicine (168:771-772) involved 51 patients with Type 2 diabetes and typical neuropathic pain. All patients were vitamin D deficient with a mean serum 25D concentration of 18 ng/mL.

    After three months, vitamin D repletion with cholecalciferol (vitamin D3) tablets resulted in a significant reduction in pain scores using two separate assessments, one suggesting the pain severity was reduced by 40% the other suggesting pain severity had been halved.

    How vitamin D reduces the severity of diabetic neuropathic pain is uncertain, but the researchers suggest that vitamin D insufficiency may potentiate diabetic nerve damage and impair nociceptor function. The results could not be explained by a decrease in parathyroid hormone as testing did not show any statistically significant difference in hormone level following the vitamin D repletion, they say.

    Vitamin D is known to have a role in the prevention of osteoporosis. It is also increasingly being recognised for its ability to improve glycaemic control, the endocrinologist researchers said. In addition, vitamin D repletion is free of adverse effects.

    Therefore, the researchers said they would advocate a trial of vitamin supplementation in vitamin D-deficient patients with neuropathic pain.

    “It is unlikely to have any harmful effects and may offer not only pain relief but also beneficial effects on bone health and glycaemic control.”

  • #2
    sup Janney, good article.

    I know how you're all into supplements...

    thought you might dig this thread...


    Started 2 days ago. so far so good.


    • #3
      Thanks Imight!

      I'm going to look into that. Makes sense.

      Keep us posted on improvements.


      • #4
        Vitamin D Update
        Vitamin D Update

        Posted on: Friday, 16 May 2008, 09:00 CDT

        We know that vitamin D helps the bones by preventing osteoporosis and fractures, but did you know that vitamin D also plays an important role in the prevention of many other diseases, including cancer, heart disease, autoimmune diseases like MS and type 1 diabetes, arthritis, infections, chronic pain and muscle weakness? Here is the latest research on this versatile vitamin:

        _Vitamin D helps pain control. A fascinating study from the Mayo clinic published last month online in the journal Pain Medicine looked at vitamin D levels in people with chronic pain. They found that those patients who had low vitamin D levels required almost twice as much narcotic pain medication compared to those with normal levels. The vitamin D deficient folks also perceived their health as poor. Another study from the Mayo Clinic in 2003 looked at the prevalence of vitamin D deficiency in people aged 10-65 with chronic pain syndromes like fibromyalgia and chronic fatigue 93 percent of them were found to be vitamin D deficient.

        _Vitamin D helps the heart. A study published last month in the journal Circulation looked at the impact of vitamin D blood levels on heart health in people with high blood pressure. Participants in the study with low vitamin D levels were two times as likely to have angina, a heart attack, heart failure and stroke compared to those with normal vitamin D levels.

        _Vitamin D reduces the risk of falls. Another study from the Archives of Internal Medicine published in March of this year looked at the effect of vitamin D supplements on falls in older women. A team of researchers in Australia gave 1,000 IU of vitamin D per day to 300 women aged 70-90, all of whom had low blood levels of D and who had also fallen in the past year. They found that in those women who had fallen once in the past year, vitamin D supplementation reduced the risk of falls, but only in the winter months when the sun's rays are weaker and less vitamin D is made in the skin. In women who had fallen multiple times, vitamin D did not seem to help, possibly because these women were more frail and were falling for other reasons.

        Who is deficient in vitamin D? Perhaps you are! Multiple studies of adults have suggested a widespread incidence of low vitamin D blood levels of less than 30 ng/ml. An adequate blood level is probably at least 40-60 ng/ml. It is estimated that 25 to 100 percent of adults are deficient, depending on the population and time of year; many children are deficient as well.

        Primitive people used to rely on sun exposure for all of their vitamin D; nowadays however, most of us work inside, and when we do go out, we slather on the sun screen which impairs our ability to make vitamin D. Older folks, people of color and people who live at higher latitudes are also at higher risk of deficiency. Most vitamin D in food, such as dairy products, does not occur naturally; it is added as a supplement, and is not considered a reliable form of intake as amounts may vary from product to product. The old recommended amounts of 200-400 IU/day are no longer considered adequate; most of us need at least 800-1,000 units per day.

        Bottom line? It may help you to take supplemental vitamin D 1,000 IU per day of vitamin D3 (cholecalciferol) should do the trick.


        • #5
          Ok it cant hurt right? I am starting my treatment of Vit D3 tomorrow - I will let you know if anything changes

          Maybe then I could cut out a med or two?? HAHA I wish
          Single mom to 5 kids who have to deal with my 4mm disc bulge, pain, nerve root damage, pain, neuropathy, pain, lt knee damage, pain, sciatica, pain, drop foot, did I mention PAIN?? Please Add us to your prayers


          • #6
            Originally posted by LuvUniformandCuffs
            Ok it cant hurt right? I am starting my treatment of Vit D3 tomorrow - I will let you know if anything changes

            Maybe then I could cut out a med or two?? HAHA I wish
            Ordererd some D3 over the weekend, hope to try it soon.