Why Don't We Have a Cure for Spinal Cord Injury? 2016

[GRAMMY]

I have a cousin working on Stem Cell Research at Michigan State. His last publication was on the natural flora and fauna in a baby's digestive tract. lol

Do you have a link to the abstract or publication to share?

[lynnifer]

I sent a DM on twitter - his sister showed me today at a grade school reunion real quick so I didn't really pay close attention. Nothing to do with spinal cord stuff.

http://www.jasonspencelab.com/

THE SPENCE LAB
The Spence lab was established in September, 2011 at the University of Michigan. We are located in the Biomedical Sciences Research Building (BSRB). The central theme of the lab is to understand how the endoderm and its associated organs develop, with a focus on intestine and lung development.

This is what my friend showed me today but she had the total article:

https://www.ncbi.nlm.nih.gov/pubmed/29110754

From a farm boy out of nowhere to big time! Good for him. lol

Another cousin is a professor of mechanical engineering at McMaster (a big health teaching hospital/university) .. worked on the Canada Arm in space.

I missed all the smart genes apparently.

[lynnifer]

Why did the anaethesiologist killer want the nurse dead?

They were having an affair and she wanted to end it. So he ended it for both of them. It was quite tragic at the time.

Not sure if you can access this or not -
https://www.pressreader.com/canada/w...81956013285655

Also this year we've had two patients attack medical staff (which led to even more security issues with metal wands).
http://windsorstar.com/news/local-ne...kplace-choking

Getting off topic - sorry peeps

[lynnifer]

This was on his twitter timeline. He's still working on this trial.

https://aospine.aofoundation.org/Str...arch&newsid=27

He also posted this latest publication a couple days ago.

https://www.ncbi.nlm.nih.gov/pubmed/29152227

A nice article again he published in Spine Universe on chronic SCI.

https://www.ncbi.nlm.nih.gov/pubmed/29152227

His TL is impressive.

Thanks for posting this! Will read tomorrow (my understanding of all this stuff is waning lol) ... I'm sitting here wondering what TL stands for ... ? It's so hard to get Canadian info - plus BC is far away from Ontario - McGill used to do a lot of research too (Quebec)

[lynnifer]

And ... I noticed that there are 15,700 views on this very topic ... yet only two pages with no real ideas. lol

[nonoise]

And ... I noticed that there are 15,700 views on this very topic ... yet only two pages with no real ideas. lol

Some of those views are mine, but I'm not SCI so I have stayed out of it until now. I have wanted to speak up every time a SCI member has stated there are so few of us as a reason for no cure. That could be a reason. It's just a depressing reason to read as I suffer a rare genetic paralysis disease that has been stated with an occurrence of 10 per million. I know of no current research or clinical trials in the USA, there is a small one in the UK for my disease. Count yourselves lucky.

[lynnifer]

What's the official diagnonsense nonoise? Would future myelin regrowing or functional electrical stim help at all?

Kinda in the same boat with Transverse Myelitis but makes me paraplegic .. just a non-traumatic paralysis.

[GRAMMY]

They were having an affair and she wanted to end it. So he ended it for both of them. It was quite tragic at the time.

Not sure if you can access this or not -
https://www.pressreader.com/canada/w...81956013285655

Also this year we've had two patients attack medical staff (which led to even more security issues with metal wands).
http://windsorstar.com/news/local-ne...kplace-choking

Weird. The article reads like a horror movie plot I'd be afraid to go see.

[GRAMMY]

Thanks for posting this! Will read tomorrow (my understanding of all this stuff is waning lol) ... I'm sitting here wondering what TL stands for ... ? It's so hard to get Canadian info - plus BC is far away from Ontario - McGill used to do a lot of research too (Quebec)

These are just links off the top of Fehlings timeline on Twitter. He's one of the most prolific tweeters working in the field. If you want to know what meetings he's attending, what his latest publications are, or articles he's writing and work he's impressed with and retweeting...just check his TL (timeline). There's tons of information there on what is happening in the SCI field along with some great photos and shout outs. It's pretty amazing!

[nonoise]

What's the official diagnonsense nonoise? Would future myelin regrowing or functional electrical stim help at all?

Kinda in the same boat with Transverse Myelitis but makes me paraplegic .. just a non-traumatic paralysis.

I love that term 'diagnonsense'. Most people just stare at me when I tell them, so here it is: https://rarediseases.info.nih.gov/di...odic-paralysis. The problem seems to be at the muscle cell wall, not the nervous system. So ya I too have a non-traumatic paralysis, except mine was sped up by breaking my hip and forced immobility.

[StemCells&AtomBombs]

re Dennis - he?s been injured as long as I have and has never taken an interest in the science or the commercial side of delivering technologies. He?s only interested in finding someone or something to agitate in order drive traffic to his blog. I don?t have the desire to enable him.

For someone who doesnt want to engage with me, you're sure good at saying my name. I'll take the public insult as you wanting to engage again.
How would I benefit from driving people to my blog? I don't make any money off it. It would be like me saying that the only reason you talk with scientists is to build your rehab business in the uk. It would be based on no fact whatsoever. So let's stick to facts and not muddy the water with innuendo.
But if my goal were driving people to my blog, I should take more mainstream positions or try to get in the cdrf blog team. Or I would just try to raise money by keeping my head underwater or running a race. Not bad ventures and sure to get a lot more attention at the moment.
I get enough public attention with my trade union work in Japan to please my ego. I don't need my blog for that.

I've always taken interest in the the science, but as I've said over and over, I don't find myself highly competent so I rely on what I learn from others, including scientists, and community members. It's the same way as why I use a lawyer for things at work. I stick with my area of ability while cooperating with others.
I make sure that when I write I supply people with links to the science instead of me trying to explain it myself. I find that those who wrote about science regularly are much better at explaining than me. It's called cooperating as a community (but more about that below)

Commercialization? You're right. Reason: I don't see that it's brought us anywhere quickly. I think most scientists, just like other academics, would like to be left alone to research so they can make their contribution to the world. I think that commercialization is something scientists/we are forced to get involved with because of the way public funds are distributed. So, I find it much easier to try to set in motion away to get public funds delivered better. I haven't accomplished this yet but neither have you cured sci your way. I think I can help effect change in this area so that's what I concentrate on. Maybe I'll fail my way or you'll fail your way. But if one of us gets a cure either way, we'll both benefit.

PS this thread is titled "Why don't we have a Cure for Spinal Cord Injury". We do not have a cure as the research field doesn't know how to regenerate the adult human chronic spinal cord.

Wow! That's the reason? It's a simple scientific issue? You're smarter than that.
That's like saying that WWII didn't effect the making of the atom bomb. Or the cold war played no role in the moon landing. Even closer to our times, like the women's movement played no role on the development and proliferation of the pill and the aids movement had no place in hastening the discovery of life saving drugs. Even a lot of the research with cells is commercialized for profit; research that would t even happen if someone didn't have a reason to make it happen.
You must have spoken to different people and scientists as I have. Whenever I've asked for what is stopping a cure, no one has ever said to me that it's only science. This is the first time I've ever heard that from anyone including yourself.

1) nobody is accountable for Cure as you cannot attach accountability to something that is undiscovered
2) there is no SCI community and therefore cannot have a value attached to it.

And finally we get your answer to your own question.
1. Was this a trick question? Yes, you're right. There is no cure yet. The point is about the accountability for FINDING a cure. Whose is this?
Id say it's the whole community of those researching a cure, those supporting a cure, and for those who would benefit from a cure.
Which leads to point 2.
2. You dont think there is an sci community? Then why are you on the site. Is it to "be educatin us simple folk"?
Why be involved in u2fp as you have or even attend w2w?
Those around you trying to achieve the same goal is what a community is, unless you believe that we're just individuals that use each other from time to time in order to meet our own individual goals?
The whole history of scientific and human progress is about community. From the first people who hunted in groups and devised better weapons together, and the industrial revolution whose two communities of both capitalists and workers lead to great advancement in science. To the current world where even the choices we make at the Ballot Box affects science.

If you think the only thing standing in the way of us standing is the lack of a scientific discovery in regeneration, then brother, you ain't half as clever as I've given you credit for.

[nrf]

“ Egotism is the anethsetic that dulls the pain of stupidity”
Frank Leahy

[StemCells&AtomBombs]

“ Egotism is the anethsetic that dulls the pain of stupidity”
Frank Leahy

As you stated a few pages ago; what does that have to do with Cure? 😀

m
Natto,
what does your post have to do with Cure?

[Fly_Pelican_Fly]

For someone who doesnt want to engage with me, you're sure good at saying my name. I'll take the public insult as you wanting to engage again.
How would I benefit from driving people to my blog? I don't make any money off it. It would be like me saying that the only reason you talk with scientists is to build your rehab business in the uk. It would be based on no fact whatsoever. So let's stick to facts and not muddy the water with innuendo.
But if my goal were driving people to my blog, I should take more mainstream positions or try to get in the cdrf blog team. Or I would just try to raise money by keeping my head underwater or running a race. Not bad ventures and sure to get a lot more attention at the moment.
I get enough public attention with my trade union work in Japan to please my ego. I don't need my blog for that.

I've always taken interest in the the science, but as I've said over and over, I don't find myself highly competent so I rely on what I learn from others, including scientists, and community members. It's the same way as why I use a lawyer for things at work. I stick with my area of ability while cooperating with others.
I make sure that when I write I supply people with links to the science instead of me trying to explain it myself. I find that those who wrote about science regularly are much better at explaining than me. It's called cooperating as a community (but more about that below)

Commercialization? You're right. Reason: I don't see that it's brought us anywhere quickly. I think most scientists, just like other academics, would like to be left alone to research so they can make their contribution to the world. I think that commercialization is something scientists/we are forced to get involved with because of the way public funds are distributed. So, I find it much easier to try to set in motion away to get public funds delivered better. I haven't accomplished this yet but neither have you cured sci your way. I think I can help effect change in this area so that's what I concentrate on. Maybe I'll fail my way or you'll fail your way. But if one of us gets a cure either way, we'll both benefit.



Wow! That's the reason? It's a simple scientific issue? You're smarter than that.
That's like saying that WWII didn't effect the making of the atom bomb. Or the cold war played no role in the moon landing. Even closer to our times, like the women's movement played no role on the development and proliferation of the pill and the aids movement had no place in hastening the discovery of life saving drugs. Even a lot of the research with cells is commercialized for profit; research that would t even happen if someone didn't have a reason to make it happen.
You must have spoken to different people and scientists as I have. Whenever I've asked for what is stopping a cure, no one has ever said to me that it's only science. This is the first time I've ever heard that from anyone including yourself.



And finally we get your answer to your own question.
1. Was this a trick question? Yes, you're right. There is no cure yet. The point is about the accountability for FINDING a cure. Whose is this?
Id say it's the whole community of those researching a cure, those supporting a cure, and for those who would benefit from a cure.
Which leads to point 2.
2. You dont think there is an sci community? Then why are you on the site. Is it to "be educatin us simple folk"?
Why be involved in u2fp as you have or even attend w2w?
Those around you trying to achieve the same goal is what a community is, unless you believe that we're just individuals that use each other from time to time in order to meet our own individual goals?
The whole history of scientific and human progress is about community. From the first people who hunted in groups and devised better weapons together, and the industrial revolution whose two communities of both capitalists and workers lead to great advancement in science. To the current world where even the choices we make at the Ballot Box affects science.

If you think the only thing standing in the way of us standing is the lack of a scientific discovery in regeneration, then brother, you ain't half as clever as I've given you credit for.

I am glad you have cleared that up. At least everyone now knows you admit to know little about the science and care even less about the role of capital markets to not only cure spinal cord injury but to move the dial on future medicines.

Every single researcher is going to say money is the #1 blocker to Cure. Of course they are. They are not going to admit that they can't figure it out are they?

If you can find me one bit of evidence to suggest a scientist anywhere in the world knows how to regenerate the adult human CNS/spinal cord I will gladly concede that science is not the problem! There is no solution to throw money at.

Yes there discoveries that have been made that will lead to incremental repair - sprouting, re-organisation, neuromodulation, increased plasticity etc. Some of these may make it to market if the right commercial people are involved and some will fall by the wayside due to various factors that are nothing to do with public monies.

Increased public monies will mean more money for the existing academic institutions involved in SCI research today. That could be a good thing if it was spent on merit and ability but the likelihood is that it will be a case of funding the same old crusty researchers in the field that have failed so far. Who will sweep away the crust?

We are in a global recession, one that sees the richest countries in the world struggle to deliver basic health needs. Without market making, lean business models and streamlined production methods spinal cord injury will never see a cure move from the bench to the bedside. Venture capital needs products to invest in. We have a dearth of good products that deserve that investment.

If anything Government money will likely follow the markets for health in the future. Incubators and commercial accelerators will grease the wheels in product development and commercialisation. But we're not there yet! Nowhere near.

The likes of Google, Facebook, Paypal and Amazon get a lot of criticism (quite rightly in some cases) but they know that the health market needs capitalism more than ever now. Billionnaires hate the thought of getting old and dying and despair at the thought of their future health being in the hands of the existing health and research systems. That is why they are now spending more money than any government could ever imagine on longevity, age-related disease and life extension health technologies free of the constraints of governments and academia.

No I am not here to educate people. I am not a teacher nor am I an expert. I post here to correct some of inaccuracies that are posted now and again.

Your definition of a community is basically a consumer. I agree we have a consumer base and demand. And one that is desperate need of a product to buy. But there is no product yet and nor is there a manufacturing pipeline for that product. I wouldn’t say it is a Community but rather a disparate group with different backgrounds, personalities, priorities and nervous system damage/characteristics. We know there isn't a silver bullet and therefore we're talking about a whole suite of products that need to be developed and brought to market. We cant look back at historical stories which have been solved by silver bullets - SCI is as multi-faceted as it's consumer base.

[nrf]

As you stated a few pages ago; what does that have to do with Cure? 

It has more to do with the lack of a cure. But I guess you don’t understand.