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Paralyzed man surprises scientists by standing and moving on his own

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  • Paralyzed man surprises scientists by standing and moving on his own

    http://www.newsweek.com/paralyzed-ma...-repair-693579

    SPINAL CORD REPAIR: PARALYZED MAN SURPRISES SCIENTISTS BY STANDING AND MOVING ON HIS OWN[/h]
    A man who was paralyzed following an extremely severe spinal cord injury has regained the ability to stand and move his limbs independently and without the need for electrical stimulation?much to the surprise of scientists working with him.
    The 32-year-old had been involved in a motorcycle accident during which he suffered from a complete spinal cord injury?meaning he had a total lack of motor function below the level of injury. The spinal cord connects the brain to almost every part of the body, so when it is damaged instructions?like telling the legs to move?cannot be communicated.
    After 21 months of rehabilitation, the patient could not walk, stand or move his legs but he then enrolled in a clinical trial involving the use of spinal cord epidural stimulation (scES). This is an approach to treating people with spinal cord injuries where a device is used to send electrical signals to motor neurons. Over the course of this study, he and three other participants had regained the ability to stand and move their lower limbs when the sdES device was activated

  • #2
    Individual with complete spinal cord injury regains voluntary motor function


    Extended activity-based training with epidural stimulation resulted in ability to stand and move without stimulation

    https://www.sciencedaily.com/release...1026103116.htm
    "Some people say that, the longer you go the better it gets the more you get used to it, I'm actually finding the opposite is true."

    -Christopher Reeve on his Paralysis

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    • #3
      The full paper in Nature is HERE
      http://spinalcordresearchandadvocacy.wordpress.com/

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      • #4
        Awesome NEWS!!!

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        • #5
          Originally posted by GRAMMY View Post
          The full paper in Nature is HERE
          They say complete paraplegic, but in the the video the man says his level was C6-C7, a quad. Interesting

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          • #6
            Originally posted by Silvio GS View Post
            They say complete paraplegic, but in the the video the man says his level was C6-C7, a quad. Interesting

            Materials and Methods Research participant.

            One of the four research participants with chronic motor complete SCI who were recruited to investigate the effects of activity-based training with scES on the recovery of lower limb motor function 18 was enrolled to perform additional activity-based training with scES at home and in the laboratory following the completion of the initial study. Research participant B13, a 32-year old male, was implanted with a spinal cord epidural stimulation unit 4.2 years afer SCI caused by a motorcycle accident. Prior to stimulator implant,this individual was unable to stand or walk independently or voluntarily move his legs despite standard-of-care rehabilitation and locomotor training received during the initial 21 months following the injury. Additional intensive locomotor training (80 sessions) performed prior to the stimulator implant did not result in functional improvements for standing, stepping or voluntary movement. Two clinicians independently performed a physical exam following the International Standards for Neurological Classification of Spinal Cord Injury 20,21 prior to stimulator implant, and classified the individual as AIS B (pinprick and light-touch present below the lesion), with a neurological level of injury at C7. In addition, as reported in a previous publication 19, no functional motor connectivity between the supra-spinal and spinal centers below the level of injury was detected in this research participant.The individual signed an informed consent for electrode implantation, stimulation, activity-based training and physiological monitoring studies approved by the University of Louisville and the University of California,Los Angeles Institutional Review Boards. All research activities were performed in accordance with the guidelines and regulations of these Institutional Review Boards. Te research participant and the other persons appearing in the Supplemental Videos included in this paper also gave written informed consent and granted full permission for their image to be used in publication online.
            http://spinalcordresearchandadvocacy.wordpress.com/

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            • #7
              I wonder if he regained bowel or bladder function

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              • #8
                Originally posted by Sparky831 View Post
                I wonder if he regained bowel or bladder function

                Using epidural stimulation, these 4 young men can voluntarily move their legs and bear weight. They all regained their ability to move in just a few weeks after being implanted with an epidural stimulator. In even bigger news, they've seen dramatic improvement in autonomic functions including bladder and bowel control, sexual function, and temperature regulation. They've also experienced improved cardiovascular and respiratory capabilities. LINK
                http://spinalcordresearchandadvocacy.wordpress.com/

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                • #9
                  How many more years lol ... will I ever pee like a normal woman again? It's been 33yrs ... lol.
                  Roses are red. Tacos are enjoyable. Don't blame immigrants, because you're unemployable.

                  T-11 Flaccid Paraplegic due to TM July 1985 @ age 12

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                  • #10
                    Have heard that for this to get to the point to help people outside of being a part of the research that it will require data on HUNDREDS. They have done 11 in 8 years. So while I am sure this will move at a faster pace then the previous 11, I can’t imagine that being less than 10-15 years, which is insane and sad.

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                    • #11
                      Have heard that for this to get to the point to help people outside of being a part of the research that it will require data on HUNDREDS. They have done 11 in 8 years. So while I am sure this will move at a faster pace then the previous 11, I can’t imagine that being less than 10-15 years, which is insane and sad.

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                      • #12
                        Oh Christ, I'll be dead by then at 60. pffft
                        Roses are red. Tacos are enjoyable. Don't blame immigrants, because you're unemployable.

                        T-11 Flaccid Paraplegic due to TM July 1985 @ age 12

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                        • #13
                          Originally posted by lynnifer View Post
                          How many more years lol ... will I ever pee like a normal woman again? It's been 33yrs ... lol.
                          The Shewee has liberated most all women (and some men)

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                          • #14
                            Originally posted by GRAMMY View Post
                            Using epidural stimulation, these 4 young men can voluntarily move their legs and bear weight. They all regained their ability to move in just a few weeks after being implanted with an epidural stimulator. In even bigger news, they've seen dramatic improvement in autonomic functions including bladder and bowel control, sexual function, and temperature regulation. They've also experienced improved cardiovascular and respiratory capabilities. LINK
                            This is really great news, but what annoys me is the amount of trials they have to do before getting it to the people who really needs something now, it takes too long. I know the tech still needs to be perfected , but if it's already proven to be safe and that it can help to a certain degree, why wait?! Just bring it out and it will get perfected even quicker....

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                            • #15
                              Originally posted by GRAMMY View Post
                              In even bigger news, they've seen dramatic improvement in autonomic functions including bladder and bowel control, sexual function, and temperature regulation. They've also experienced improved cardiovascular and respiratory capabilities. LINK
                              Last time, many years ago, when they reported on the original four, they found the same thing. At that time though it was a shock and had not set up to measure these gains. I've looked endlessly to find if they would be measuring these gains this time as it would no longer be a mystery but have never found if they would measure it. Sadly, the Nature article also didn't mention it.
                              The report this time, regarding BBS, mentioned casually on the website, is no different than last time. BBS is right at the top of the list just under breathing for many paralysed folks so I'm wondering why they wouldn't (if they didn't) monitor it's return.
                              I'm left with the same question that I had four or five years ago (or was it even longer when the first four reported) of what "bladder and bowel control" means.
                              Does anyone know where I could find more about BBS in this trial? Believe me, I have looked

                              For years there have been numerous surveys conducted amongst the spinal cord injured community about what issues are important (I believe they were often done to prove that those with SCI were NOT interested in full functional return). Knowing that BBS is so important, you'd figure that they would have monitored it.

                              Here is some background on some of these surveys. I couldn't find all of the ones I wanted.
                              http://stemcellsandatombombs.blogspo...riorities.html
                              http://stemcellsandatombombs.blogspo...s-by-rick.html
                              Last edited by StemCells&AtomBombs; 10-28-2017, 09:15 AM.
                              Dennis Tesolat
                              www.StemCellsandAtomBombs.blogspot.com

                              "Change does not roll in on the wheels of inevitability, but comes through continuous struggle. And so we must straighten our backs and work for our freedom."
                              Martin Luther King

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