Announcement

Collapse
No announcement yet.

ReNetX Bio Launched to Advance Innovative Neuro-Regenerative Technology Developed at

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

    #31
    "When Strittmatter put this molecule into the spinal fluid of rats with damaged spinal cords—nearly a third went from not being able to walk to full mobility, even after a three-month delay period between injury and treatment. Findings were published in the Journal of Neuroscience (link is external) and Nature (link is external) among others."

    Exciting news but I'm curious as to what they mean by "full mobility". To me that's a cure though I'd assume it's far less. Anyone know, or any guesses as to how they define full mobility?

    Comment


      #32
      It won't be a full cure as the growth doesn't happen through the scar. The results should be even better when Chase is available.

      Comment


        #33
        Originally posted by tumbleweeds View Post
        "When Strittmatter put this molecule into the spinal fluid of rats with damaged spinal cords—nearly a third went from not being able to walk to full mobility, even after a three-month delay period between injury and treatment. Findings were published in the Journal of Neuroscience (link is external) and Nature (link is external) among others."

        Exciting news but I'm curious as to what they mean by "full mobility". To me that's a cure though I'd assume it's far less. Anyone know, or any guesses as to how they define full mobility?

        Interesting... Intrathecal delivery, not intraspinal... I tend to dismiss studies using Intrathecal injections off rip but could there be something to it
        "That's not smog! It's SMUG!! " - randy marsh, southpark

        "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


        2010 SCINet Clinical Trial Support Squad Member
        Please join me and donate a dollar a day at http://justadollarplease.org and copy and paste this message to the bottom of your signature

        Comment


          #34
          Does anyone know what Asia group(s) they plan on doing their chronic trial with?

          Comment


            #35
            Originally posted by nphuskers View Post
            Does anyone know what Asia group(s) they plan on doing their chronic trial with?
            Ask Mize he might know! He's going to be an investor.

            Comment


              #36
              Originally posted by nphuskers View Post
              Does anyone know what Asia group(s) they plan on doing their chronic trial with?
              Not announced yet. They're still doing fundraising.
              http://spinalcordresearchandadvocacy.wordpress.com/

              Comment


                #37
                Originally posted by Sparky831 View Post
                Ask Mize he might know! He's going to be an investor.
                Ha! We shall see about that one. There are a tremendous number of hurdles from where they are today to human trials. If all goes swimmingly they could have neat stuff in a few years, but it could take longer or not even work in humans. That said, I'm excited and following it.
                T3 complete since Sept 2015.

                Comment


                  #38
                  Originally posted by Mize View Post
                  There are a tremendous number of hurdles from where they are today to human trials.
                  What are the hurdles?

                  Comment


                    #39
                    From memory, the hurdles stem from inhibiting three growth inhibitors; what else gets going besides axon growth and nerve sprouting? Is there a increased cancer risk? What are the other side-effects?
                    I'll try to track down my notes because the deck doesn't include the stuff we talked about on the phone.
                    T3 complete since Sept 2015.

                    Comment


                      #40
                      Originally posted by Mize View Post
                      From memory, the hurdles stem from inhibiting three growth inhibitors; what else gets going besides axon growth and nerve sprouting? Is there a increased cancer risk? What are the other side-effects?
                      I'll try to track down my notes because the deck doesn't include the stuff we talked about on the phone.
                      Ah, ok. I thought you meant there were things stopping the trial that they hadn't mentioned to me.

                      Comment


                        #41
                        Originally posted by nphuskers View Post
                        Does anyone know what Asia group(s) they plan on doing their chronic trial with?
                        I've been told the phase 1 trial is for chronic (more than 12 months) cervical injuries, ASIA-A and ASIA B. Phase 2 is planned to expand on the criteria.

                        Comment


                          #42
                          Originally posted by Mize View Post
                          From memory, the hurdles stem from inhibiting three growth inhibitors; what else gets going besides axon growth and nerve sprouting? Is there a increased cancer risk? What are the other side-effects?
                          I'll try to track down my notes because the deck doesn't include the stuff we talked about on the phone.
                          I asked the question and was told that the preclinical safety studies have not indicated that there is a concern with cancer or non-beneficial sprouting. There shouldn't be any delays due to safety concerns.

                          Comment


                            #43
                            Originally posted by niallel View Post
                            I've been told the phase 1 trial is for chronic (more than 12 months) cervical injuries, ASIA-A and ASIA B. Phase 2 is planned to expand on the criteria.
                            Who told you this? Did they tell you this recently (this year)?

                            Comment


                              #44
                              Originally posted by Sparky831 View Post
                              Who told you this? Did they tell you this recently (this year)?
                              I heard this yesterday from the Executive Director who owns this from Wings for Life. She verified it with RenetX before coming back to me.

                              I could have asked Erika Smith or Stephen Strittmatter, but I thought this would be the quickest route to the answers.

                              Comment


                                #45
                                Originally posted by niallel View Post
                                I heard this yesterday from the Executive Director who owns this from Wings for Life. She verified it with RenetX before coming back to me.

                                I could have asked Erika Smith or Stephen Strittmatter, but I thought this would be the quickest route to the answers.
                                Nice thank you for letting us know! Do you know if there's going to be a limit on the amount of years since the injury? I hope there's no limit

                                Comment

                                Working...
                                X