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  • Originally posted by paolocipolla View Post
    Rumors are that soon they will recruit the next patient in Poland with chronic SCI with an almost transected spinal cord.
    Then it seems that in 2017 a trial in London will start, but that will be on acute SCI. If that is true it will be very disappointing for people with chronic SCI.
    That would make two chronic (both sharp instrument knife wounds) and one acute. Who exactly plans on funding a London 2017 acute trial?
    http://spinalcordresearchandadvocacy.wordpress.com/

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    • Originally posted by GRAMMY View Post
      That would make two chronic (both sharp instrument knife wounds) and one acute. Who exactly plans on funding a London 2017 acute trial?
      That's not clear to me yet.
      In God we trust; all others bring data. - Edwards Deming

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      • Any word on this technique being tested any further? Clinical trials etc?

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        • Seems like one of the main scientists related to this technique has died
          https://www.theguardian.com/science/...isman-obituary

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          • Originally posted by greenseed View Post
            Any word on this technique being tested any further? Clinical trials etc?
            https://walk-again-project.org/#/en

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            • Still looking for acute clean cut knife wounds...

              RESEARCH QUALIFICATION CRITERIA

              • traumatic severance of the spinal cord, e.g. due to injury caused by a sharp object
              • confirmation of the severance of the spinal cord in magnetic resonance imaging (MRI)
              • total absence of all types of sensation and voluntary muscle mobility in areas provided for by the spinal cord below the point of damage (damage level ASIA A, Frankel A – in the event of uncertainty, the patient should seek the opinion of a local neurologist/neurosurgeon regarding the damage severity level)
              • age from 16 to 65 years
              • patient undergoing constant physiotherapy
              • high motivation and willingness to cooperate, no mental disturbances
              • willingness to spend three years (with breaks) in Poland (together with accompanying person)
              http://spinalcordresearchandadvocacy.wordpress.com/

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              • Does that qualification include the willingness to let them open your head to get the cells from near your brain?

                As with all trials I'm desperate for them to succeed, but unless they can find a better way of getting the cells I can't see it taking off.
                I would have thought solving the problem of how they get the cells would be a better start, if they can't get them in a less invasive way then why continue?

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                • Thanks Sparky and Grammy. Only for cords severed with sharp objects hey? I wonder why? Smaller lesion?

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                  • I can cut mine, won't make any difference now.

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                    • Originally posted by greenseed View Post
                      Thanks Sparky and Grammy. Only for cords severed with sharp objects hey? I wonder why? Smaller lesion?
                      Well, perhaps. The clean cut is very thin and even. In a contusion injury, the site has broken axons splayed out and stretched in all directions. Usually resulting in lots of damage and the axons are no longer pointing in the direction in which they need to grow and reconnect. (This was in part why there was difficulty with replicating and translating the Davies animal studies). He was making very fine minuscule knife cuts to the cord rather than a more true to life SCI injury with a gauged impactor. I believe there has been much improvement with standardized injury models over the years.
                      http://spinalcordresearchandadvocacy.wordpress.com/

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                      • Originally posted by niallel View Post
                        I would have thought solving the problem of how they get the cells would be a better start, if they can't get them in a less invasive way then why continue?
                        The surgery is indeed gruesome. They were at one time supposedly experimenting on cadavers to minimize the damage. I'm not sure where all that ended up.
                        http://spinalcordresearchandadvocacy.wordpress.com/

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