Announcement

Collapse
No announcement yet.

Lou Gehrig's disease patient: Brainstorm Cell treatment helped me

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

    Lou Gehrig's disease patient: Brainstorm Cell treatment helped me

    Avichai Kremer is the first patient to be treated with Brainstorm Cell's drug, NurOwn, on the basis of a special approval.
    http://www.globes.co.il/serveen/glob...70741&fid=1725

    #2
    "A successful treatment opens the $1 billion a year ALS market before the company."

    money money money - and it would be kinda nice to save the lives of those unfortunate people who get this disease

    Comment


      #3
      I just met a woman with ALS this past Wednesday. She has had it for 2 yrs and now her throat is paralyzed. She is very moble, but can't talk, eat or swallow. She has to have a feeding tube and must spit out all saliva. It is so sad....yet I asked her if she would trade places with me (since she walks perfectly fine now) and she nodded yes. Once again, God puts me in a situation where I must look at my injury and conclude that there really ARE worse things that could happen.

      Comment


        #4
        I attended a memorial service a couple weeks ago for a 48 year old friend who died from ALS. It's a cruel cruel disease.

        Comment


          #5
          Israeli Clinical Study Offers Hope to ALS Patients
          "Our 'trick' is causing the cells to differentiate so that they secrete proteins that are important for communication between muscles and nerves. Scientists think that in ALS there is a discontinuation of communication between muscle and nerve."
          http://www.bridgesforpeace.com/modul...ticle&sid=8137

          Comment


            #6
            What hopefull news! My wife has lost her mother, a few aunts, uncles and distant cousins to ALS. Her maternal family, the Lawrences, are working on genetic research @ Univ. Of S. Illinois re: ALS due to so many instances in their bloodline.
            "I have great faith in fools; self-confidence my friends call it." - Edgar Allen Poe

            "If you only know your side of an issue, you know nothing." -John Stuart Mill, On Liberty

            Comment


              #7
              Good news. Hope other patients also get recovery from this treatment.

              This treatment can work as neuronal replacement for lower spinal injuries too i guess.

              Comment


                #8
                BrainStorm readies ALS stem cell testing in U.S.
                http://biotuesdays.com/2011/12/13/br...esting-in-u-s/
                “The ability to induce differentiation into neuronal-like cells, with delivery either into muscle tissue at the site of damage, the brain or into the spinal cord makes our technology highly attractive for treating ALS and Parkinson’s disease as well as multiple sclerosis and spinal cord injury,” Dr. Harel contends. He adds, “We are focusing on CNS disorders only, and ALS is our first indication.”

                Comment


                  #9
                  "Proposed Trial Will Build on NurOwn™ Platform to Meet Unmet Needs of Patients with Neurodegenerative Disorders"
                  http://www.businesswire.com/news/hom...itiation-Study

                  Comment


                    #10
                    kivi, I notice they use mesenchymal cells for their therapy. I remember Dr Weissman of Stem Cell INc said that they didn't think those cells would work. who knows, just thought I'd mention it for our use.

                    Anthony

                    Comment


                      #11
                      Yes, Anthony, the first possible effective therapy using the mesenchymal stem cells is targeted to ALS and MS (in neurology), but "These findings provide support once again that BrainStorm’s MSC-NTF secreting cells have the potential to become a platform that in the future will provide treatment for various neuro-degenerative diseases," says Chaim Lebovits, President of BrainStorm. "This study follows previously published pre-clinical studies that demonstrated improvement in animal models of neurodegenerative diseases such as Parkinson’s, Multiple Sclerosis (MS) and neural damage such as optic nerve transection and sciatic nerve injury. Therefore, BrainStorm will consider focusing on a new indication in the near future, in addition to the ongoing Clinical Trials in ALS.” http://www.sciencedirect.com/science...14488612000295
                      and "The NurOwn? technology processes autologous adult human mesenchymal stem cells that are present in bone marrow and are capable of self-renewal as well as differentiation into many other cell types. Adult human bone marrow cells are induced to differentiate into astrocyte-like cells capable of releasing neurotrophic factors, including glial-derived neurotrophic factor (GDNF) by means of a specific differentiation-inducing culture medium. The ability to induce differentiation into astrocyte-like cells along with intramuscular or intrathecal (or other) delivery makes NurOwn? technology highly attractive for treating ALS and Parkinson's disease as well as MS and spinal cord injury." http://www.4-traders.com/BRAINSTORM-...cy-o-13972622/ ;
                      http://video.cnbc.com/gallery/?video=3000074883# (from the second minute)
                      http://www.youtube.com/watch?v=0aE2f...5BE003DC270888

                      Comment


                        #12
                        kivi, yes,Ireadmore about it and it looks good. Just wondering if they don't work for spinal injuries as per Stem Cell Inc or is there more to learn.
                        anyway, bottom line, let's hope it works for als and ms; those people need something.

                        Anthony

                        Comment


                          #13
                          I would never ask anyone, anywhere about an SCI cure, ever, if they could cure ALS.

                          Evil, evil, evil shit.
                          And the truth shall set you free.

                          Comment


                            #14
                            Originally posted by NoDecafPlz View Post
                            I would never ask anyone, anywhere about an SCI cure, ever, if they could cure ALS.

                            Evil, evil, evil shit.

                            I am sorry. I didn't understand what you are trying to say
                            "That's not smog! It's SMUG!! " - randy marsh, southpark

                            "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


                            2010 SCINet Clinical Trial Support Squad Member
                            Please join me and donate a dollar a day at http://justadollarplease.org and copy and paste this message to the bottom of your signature

                            Comment


                              #15
                              It is a little early to make any claims about recovery... Read what the article says...

                              http://www.globes.co.il/serveen/glob...70741&fid=1725


                              In a letter obtained by "Globes", Avichai Kremer stated, "I was diagnosed (with ALS) seven years ago at age 29. Today I am almost completely paralyzed and can’t walk, talk, or eat (I use a feeding tube). I am writing this letter using my head. ALS/MND has no effective treatment and diagnosis means a death sentence even today, a decade into the 21st century.

                              "Nevertheless, I was fortunate to be the first to get the stem cells treatment of Brainstorm Cell Therapeutics two and a half months ago (October 2010) at Hadassah hospital in Jerusalem, Israel. The procedure was simple and quick. Within 24 hours I was back home. Two and a half months later, I can testify that the Brainstorm treatment is completely safe and that my condition didn’t deteriorate in that time. In fact, not only did the disease seem to slow/stop in that time period, but preliminary follow-up tests done at Hadassah showed slight improvement in several physical functions such as breathing and speech."

                              Kremer is the first patient to be treated with Brainstorm Cell's drug, NurOwn, on the basis of a special approval. The treatment is not part of the clinical trials that are conducted to establish statistical analyses of a drug's efficacy and safety. The company is currently conducting a Phase I/II clinical trial of the drug.

                              Treatment with a drug without US Food and Drug Administration (FDA) or Ministry of Health approval of a single patient is an extraordinary procedure, given in incurable diseases. Such cases are usually handled at the medical center that is also conducting the clinical trial, and the results are not always sent to the company that is developing the drug.

                              Brainstorm Cell initiated the clinical trial of NurOwn last month, and is currently selecting patients for participation. If the treatment is successful, it could be a historic achievement, as there is no treatment for ALS, and sufferers die within 2-5 years. However, success in a single patient often cannot be replicated, and is statistically meaningless in a clinical trial and have no bearing on approval of the drug.

                              Comment

                              Working...
                              X