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  • Ohio Spinal Cord Injury Victims Getting a Better Outlook

    Thousands of Americans sustain traumatic spinal cord injuries every year. Learn more about some of the common causes, and the new treatments being developed.

    August 10, 2011 /24-7PressRelease/ -- Ohio Spinal Cord Injury Victims Getting a Better Outlook

    Spinal cord injuries impact the lives of thousands of Americans every year. Damage to sensitive nerve tissues can result in partial or total paralysis, making day to day activities a challenge for many victims. But, some companies are developing innovative treatments that offer renewed hope to patients who have suffered extensive spinal cord injuries.

    The New Techniques
    read...

    http://www.24-7pressrelease.com/pres...ook-228461.php

    Comment


    • silver new treatment

      "Silver Helps Regrow Tissues in Hundreds of Patients - Destroyed Cells Regenerate With Silver-Based Procedure"
      by Samuel Etris
      Senior Technical Consultant to The Silver InstituteSilver can help regenerate human cells that have been destroyed by disease or damaged in accidents.
      The silver-based procedure has been so successful in clinical tests, that one patient who had sustained three crushed fingers in an accident grew new tissue immediately. Within 2-1/2 months, skin coverage was complete and there was normal, full sensation, good blood supply and all joints had a normal range of motion. If left untreated, the 3~year-old electrician's fingers would have fallen off after turning black with gangrene, and he would have been left with a totally useless hand. In fact, his orthopedic surgeon recommended amputation of al1 three fingers, but the patient requested silver-ion therapy that was successful.
      The mechanism by which silver ions help rebuild tissue has been studied for more than a decade by Robert O. Becker, M. D., Becker Biomagnetics, Lowville, New York. Becker first reported his findings at the First International Conference on Silver and Gold in Medicine, cosponsored by The Silver Institute in 1987.
      In the decade since, this technique has been used in a clinical setting at Mountain Medical Specialties in Lakemont, Georgia, where hundreds of patients with various wounds have recovered. In addition, a laboratory study conducted by the U.S. Army Institute for Surgical Research in Fort Sam Houston, Texas, showed that laboratory animals with burn wounds treated under controlled conditions experienced shortened time for reconstruction with silver-nylon dressings. Recovery of skin function was faster when electric current was applied compared to no application of electric current.
      Becker discovered that when positively charged silver ions are electrically introduced into wounds with a proprietary silver-coated nylon fabric used as the positive electrode, large amounts of primitive embryonic stem cells are produced. These stem cells are responsible for the reconstruction of destroyed tissue at a pace considerably faster than if the wound had been left to heal by itself. In other cases, the wound might not heal at all without the introduction of these stem cells
      "The advantages of this technique," says Becker, "are the ease of use, use of the patient's own cells, no immune reaction, no need to use human fetusus as a source of stem cells, no need for anti-rejection drugs and it is economic." [bag - the pharmas just hate that]
      On September 29, 1998, Becker received a U.S. patent (5,814,094) for the devices, materials and techniques involved in regeneration of tissue using silver ions.
      After several hundred cases, Becker believes that the technique works in three stages. The first stage is the chemical combination of the highly active free silver ions with all bacteria or fungi present in the wound that are inactivated within 20 to 30 minutes. The second stage occurs over the next few days. Silver acts on fibroblast cells (the cells that normally cause wound healing by scar formation) to cause them to revert to their embryonic state, becoming stem cells. These cells are universal building blocks whose role is to reconstruct new tissue regenerating the original structure rather than simply to form scar tissue only.
      In the final stage, silver ions form a complex with the living cells in the wound area to produce immediately convertible stem cells. As stem cells flood the wound, they are rapidly converted into new, mature normal tissues of the types present before the wound occurred. The end result of this conversion is complete restoration of all anatomical structures including nerves and blood supply with no scar formation. In all cases treated, no evidence of argyria (discoloration of skin) or any other side effect was noted.
      No other known treatment provides sufficient numbers of the embryonic or stem cells required for true regeneration of damaged or destroyed tissue in humans and animals. This success indicates that there is the potential not only for the healing of near-surface wounds, but for regenerative repair of internal organs such as the heart, liver, brain and the spinal cord.
      I am not your rolling wheels
      I am the highway
      I am not your carpet ride
      I am the sky
      I am not your blowing wind
      I am the lightning
      I am not your autumn moon
      I am the night, the night..

      Comment


      • a little more,

        http://utsurg.uth.tmc.edu/pedisurger.../levine-cv.htm

        http://utsurg.uth.tmc.edu/pedisurger...-clinical.html

        Safety of Autologous Mesenchymal Stem Cell Therapy for Spinal Cord Injury in Children
        This is a FDA approved pilot study, conducted at Children’s Memorial Hermann Hospital and sponsored in part by TIRR, to determine if bone marrow harvest and transplantation are safe in children with SCI. Ten children, ages 0-15 years of age who have suffered a SCI within 6 months to 4 years of study enrollment, will undergo bone marrow aspiration. Following cell processing, the children will then receive an Intravenous infusion of their cells. They will return at 30 days and 6 months post-procedure for follow-up to assess late functional outcome using pre-transplantation spinal cord function as the control.
        Safety of Autologous Human Cord Blood as a Treatment for Traumatic Brain Injury in Children
        This is a FDA approved pilot study, conducted at Children’s Memorial Hermann Hospital and sponsored in part by Cord Blood Registry (CBR), to determine if autologous hUCB transplantation for TBI is logistically feasible and safe. Ten children, ages 18 months -17 years who have suffered a severe to moderate TBI 6 months to 18 months prior and who have their own cord blood banked at CBR, will receive an intravenous infusion of their cord blood derived cells. Follow-up will occur at 6 months, 1 year and 2 years post-procedure to assess improvement using pre and post-TBI neuropsychological and imaging outcomes measures.

        -----------------------
        wow, almost 1 million

        anyone know about this researcher or live near his lab

        Quote:
        Originally Posted by manouli View Post
        Published Sunday, August 07, 2011 12:07 AM
        Texas A&M team granted funding
        By MICHELLE CASADY
        michelle.casady@theeagle.com


        Less invasive and more successful treatments for people with spinal cord injuries could be available soon, in part because of research that's scheduled to begin this October at the Texas A&M College of Veterinary Medicine and Biomedical Sciences.

        The Department of Defense awarded a $900,000 competitive grant to a team of researchers, led by Jonathan Levine, who is an assistant professor in neurology at the CVM.

        The team will also collaborate with researchers at the University of California San Francisco.

        It is hoped that the study of naturally occurring spinal cord injuries in dogs will lead to better treatments for humans.

        "What's been done in labs across the country is the study of spinal cord injuries in rodents, where the spinal cord is traumatized purposefully, and then treatments are given," Levine said. "But the 70 or so treatments in rodents that have shown promise, when they're taken to human clinical trials, very few have worked."



        read....

        http://www.theeagle.com/local/A-amp-...ranted-funding
        http://justadollarplease.org/

        2010 SCINet Clinical Trial Support Squad Member

        "You kids and your cures, why back when I was injured they gave us a wheelchair and that's the way it was and we liked it!" Grumpy Old Man

        .."i used to be able to goof around so much because i knew Superman had my back. now all i've got is his example -- and that's gonna have to be enough."

        Comment


        • Published: Friday, Aug. 12, 2011 / Updated: Friday, Aug. 12, 2011 02:28 PM
          Leading Spinal Cord Injury Researcher, James A. Krause, Ph.D., to Receive 2011 Medtronic National Courage Award
          Courage Center
          MINNEAPOLIS, Aug. 12, 2011 --

          /PRNewswire/ -- James S. Krause, Ph.D., a Minnesota native, is the 2011 recipient of the Medtronic National Courage Award presented by Courage Center. Dr. Krause, a professor and associate dean for Research in the College of Health Professions at the Medical University of South Carolina (MUSC) in Charleston, is a leading national expert and research psychologist who specializes in adjustment following a spinal cord injury.

          The award is especially meaningful to Krause, who has a spinal cord injury at the C6-7 level. From 1976-79, he was a patient at Courage Center's Transitional Rehabilitation Program (TRP), known then as Courage Residence. A three-year inpatient stay at Courage Center was common during in the 1970s and 1980s. Today, the average length of stay for someone with a spinal cord injury is 99 days.



          Read more: http://www.heraldonline.com/2011/08/...#ixzz1Us2PsKyA

          Comment


          • Drug could heal spinal injuries
            by ANDREA PERRY, femail.co.uk

            People who are permanently paralysed - like Superman actor Christopher Reeve - may one day be able to take a drug which will repair spinal injuries.

            Although the research is still in its infancy, scientists believe they have found the key to regenerating damaged nerve cells.

            The discovery might eventually lead to the development of a drug which will enable the central nervous system to repair itself after injury.

            Broken spinal cords could grow back together and it may also be possible to repair brain injuries caused by strokes or blows to the skull, or halt the devastating progression of multiple sclerosis.

            more...

            http://www.dailymail.co.uk/health/ar...-injuries.html

            Comment


            • Savannah para/quadriplegics at YMCA seek to expand program
              Posted: August 15, 2011 - 4:03pm

              By Chris Kardish Copyright 2011 . All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

              read this article here:

              http://savannahnow.com/latest-news/2...expand-program
              Last edited by manouli; 08-15-2011, 06:56 PM.

              Comment


              • InVivo Therapeutics Treats the Spinal Cord Itself, A Novel Technology
                Posted by iCELL News, on 15th August 2011, in Stem Cell Research.

                InVivo Therapeutics Treats the Spinal Cord Itself, A Novel Technology

                Written by Herina Ayot on Aug 15, 2011

                Print PDF

                Frank Reynolds, President and CEO of InVivo Therapeutics was interviewed by OneMedRadio where he describes the company’s strategy in bringing its unique spinal cord injury (SPI) products to market.

                Brett Johnson: Good day. This is Brett Johnson with OneMedRadio in New York City. Today, I’m with Frank Reynolds who is the CEO of InVivo Therapeutics, a Cambridge, Massachusetts Company that develops treatments to improve function for those paralyzed as a result of traumatic spinal cord injury. The company was founded in 2005 with a technology developed at MIT. It’s traded on the bulletin board at NVIV.

                The company recently announced that they had submitted an investigational device exemption to the FDA for a device to protect spinal tissue and prevent secondary injury following traumatic spinal cord injury. Thanks for joining us today, Frank.

                Frank Reynolds: Thank you very much for having me.

                BJ: Can you tell us first a little bit about InVivo the business and the significance of your submission to the FDA and what this might mean for InVivo?

                FR: Sure. So today, there is no treatment for spinal cord injury other than treating from trauma to areas around the spinal cord itself. So there will be spinal fixation devices and maybe anti-inflammatory treatments to try and calm, you could say, the areas outside of the spinal cord. But there actually isn’t a treatment that actually is implanted into the spinal cord itself.

                So we’ve submitted an application that doesn’t involve any drugs or cells that has only a one-year patient follow-up and we believe this treatment will provide neural protection as you mentioned earlier and then of course support neuroplasticity and regain levels of functioning in the patients in as fast as say four weeks after injury. So we’re very excited about the product. The product is also a true platform technology. So we have used the same product along with say human neural stem cells and had successfully treated monkeys with the human neural stem cells. So the first product we have submitted to the FDA will become a true platform to enable the delivery of other drugs and cells in a variety of different forms and in the end we should be able to treat just about every type of spinal cord injury there is.

                BJ: When do you find out from the FDA the status of the exemption?

                continue...

                http://investorstemcell.com/stem-cel...el-technology/

                Comment


                • Leading Spinal Cord Injury Researcher, James S. Krause, Ph.D., to Receive 2011 Medtronic National Courage Award


                  Information contained on this page is provided by companies via press release distributed through PR Newswire, an independent third-party content provider. PR Newswire, WorldNow and this Station make no warranties or representations in connection therewith.

                  SOURCE Courage Center

                  MINNEAPOLIS, Aug. 15, 2011 /PRNewswire/ -- James S. Krause, Ph.D., a Wadena Minnesota native, is the 2011 recipient of the Medtronic National Courage Award presented by Courage Center. Dr. Krause, a professor and associate dean for Research in the College of Health Professions at the Medical University of South Carolina (MUSC) in Charleston, is a leading national expert and researcher who specializes in health and longevity following a spinal cord injury.

                  The award is especially meaningful to Dr. Krause, who has a spinal cord injury at the C4-5 level. From 1976-79, he was a patient at Courage Center's Transitional Rehabilitation Program (TRP), known then as Courage Residence. A three-year inpatient stay at Courage Center was common during in the 1970s and 1980s. Today, the average length of stay for someone with a spinal cord injury is 99 days.

                  "With numerous medical rehabilitation and assistive technological advancements in the past 25 years, our client's length of stay in the TRP has been dramatically reduced," said Martha Swenson, senior director, Transitional Rehabilitation Program. "Our program continues to be based on a holistic approach to rehabilitation with the belief that our clients can realize their full potential in every aspect of life."

                  more...

                  http://www.wlns.com/story/15268494/l...type=printable

                  Comment


                  • Rugby stars raise over $200,000 for spinal cord injury research and rehabilitation

                    Rugby stars raise over $200,000 for spinal cord injury research and rehabilitation
                    Posted on August 16, 2011 by centreforbrainresearch| Leave a comment
                    What an amazing night we had on Friday! Our top scientists joined sports stars from all over New Zealand to raise money for spinal cord injury.

                    ← Getting spinal injury victims back on their feet
                    Rugby stars raise over $200,000 for spinal cord injury research and rehabilitation
                    Posted on August 16, 2011 by centreforbrainresearch| Leave a comment
                    What an amazing night we had on Friday! Our top scientists joined sports stars from all over New Zealand to raise money for spinal cord injury.


                    From L-R: Communications Manager Laura Fogg, SCIRU leader Professor Louise Nicholson, All Blacks captain Richie McCaw, and Brain Bee organiser Johanna Beattie

                    Hosted by The Black Friday Trust at the Langham Hotel, the event was called “Believe”, and more than lived up to its name as guests gave, and kept on giving, to three recipient charities: CatWalk (research), The Spinal Trust (rehabilitation) and the New Zealand Rugby Foundation (prevention and support).

                    Around $200,000 was raised for two important causes; upgrading the Auckland Rehabilitation Unit and supporting the newly-established Spinal Cord Injury Research Unit (SCIRU) based here at the Centre for Brain Research. SCIRU is led by Professor Louise Nicholson, who was there at the dinner, and forms part of the Integrative Neuroscience Facilities led by Associate Professor Bronwen Connor. The unit was established by the Catwalk Trust with the aim of finding a cure for spinal cord injury (SCI).

                    read...

                    http://centreforbrainresearch.wordpr...ehabilitation/

                    Comment


                    • Natural self-repair mechanisms that kick in soon after spinal cord damage recognized

                      Natural self-repair mechanisms that kick in soon after spinal cord damage recognized
                      August 18th, 2011 admin Posted in Healthcare News | No Comments »



                      — scientists within the college of Alberta’s Faculty of Rehabilitation medication have designed a vital discovery that might cause much more helpful treatment options for spinal-cord injuries. Karim Fouad and David Bennett have recognized a single on the body’s all-natural self-repair mechanisms that kick in soon after damage.

                      To assist recognize the discovery the scientists say it is actually essential to initial illustrate the neurons within the spinal cord that manage muscle contractions. These neurons symbolize a reasonably autonomous component on the nervous process that manage several fundamental capabilities like as strolling and bladder manage. These neurons are introduced right into a state of readiness by a transmitter referred to as serotonin. Serotonin originates within the brain and tasks down the spinal cord exactly where it binds to serotonin receptors about the neurons. This approach turns a tranquil neuron into a single that is prepared to reply to rapid inputs from your brain.

                      read...

                      http://ihnma.com/2011/08/18/natural-...ge-recognized/

                      Comment


                      • "Spinal Cord Injury - Pipeline Review, Q3 2011" now available at Fast Market Research



                        2011-08-19 06:29:58 - Fast Market Research recommends "Spinal Cord Injury - Pipeline Review, Q3 2011" from Global Markets Direct, now available


                        Spinal Cord Injury - Pipeline Review, Q3 2011

                        Summary

                        Global Markets Direct's, 'Spinal Cord Injury - Pipeline Review, Q3 2011', provides an overview of the Spinal Cord Injury therapeutic pipeline. This report provides information on the therapeutic development for Spinal Cord Injury, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Spinal Cord Injury. 'Spinal Cord Injury - Pipeline Review, Q3 2011' is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team.

                        read...

                        http://www.pr-inside.com/spinal-cord...w-r2770731.htm

                        Comment


                        • New Treatments for Brain and Spinal Cord Injuries.

                          Aug 20, 2011
                          Dinah JL Novak

                          Biomaterials with the aid of nanomedicine and stem cell are the key elements to restore CNS disorders

                          In the near future nanogenerators will support nanorobots with the capability to repair DNA and to restructure impaired neurones and their organelles through gene regulation (gene expression specificity) to reactivate their molecular conformation and tasks.



                          Read more at Suite101: New Treatments for Brain and Spinal Cord Injuries. | Suite101.com http://www.suite101.com/content/new-...#ixzz1VdRIe7QK

                          Comment


                          • Stem Cell Treatment for Spinal Cord Injuries: The New Frontier
                            by ray on Sunday, August 21st, 2011 | No Comments

                            Stem Cell Treatment for Spinal Cord Injuries: The New Frontier

                            Although the hard bones of the spinal column protect the soft tissues of the spinal cord, vertebrae can still be broken or dislocated in a variety of ways and cause traumatic injury to the spinal cord. Spinal cord injuries vary in their severity, but almost inevitably lead to various forms of compromised functionality as the spinal cord is in effect the main pathway for information to travel around the human body. Precisely what body functions are impaired by the injury will depend on the area of the spine that has been damaged and the extent to which the spine has been affected. Although serious impacts such as falls and motor vehicle accidents account for many spinal cord injuries, tumors growing close to the column can also damage sensitive nerve tissue and have the same effects.

                            For decades scientists have been working to try and find a way to remedy the various ailments that spinal cord injuries can bring, but with limited success. However, in recent years a pioneering new technology has emerged that is helping thousands of people around the world regain part, if not all, of their previously lost mobility. That treatment is the use of stem cells.

                            What are Stem Cells and Stem Cell Treatments?

                            Stem cells are found in all multi cellular organisms and are characterized by their ability to differentiate into a diverse range of specialized cells when they divide and renew themselves. They are remarkable for their ability to regenerate themselves into almost any other human cell. Their use in the treatment of various diseases and conditions, from Leukemia to Multiple Sclerosis, is now becoming more common. Depending on the condition, stem cells can be transplanted into the patient to help renew and regenerate previously damaged cells, giving patients renewed hope when, before, no reliable treatment existed.

                            This principle is now being applied to the treatment of spinal cord injuries using stem cells, and in instances where the patient has not experienced a complete spinal cord injury, i.e. a complete severing of the spinal cord leading to a loss of function below the ‘neurological’ level. There has been great success in helping patients recover greater sensory and physiological ability.

                            Spinal Cord Injury: How Stem Cell Treatment Works

                            When there is trauma to the spinal cord, myelopathy (damage to the fibres that carry messages to and from the brain) has occurred. These ‘myelinated fibre tracts’ are the focus of stem cell treatment, and are the nerve cells that the treatment helps to regenerate. The procedure usually follows three phases and usually requires no longer than a period of around five weeks in medical care for monitoring:

                            Phase one involves the harvesting of stem cells. The cells are extracted from a fetus’s umbilical cord. They are then put through a process whereby they are isolated and purified before they are finally cultured to be suitable for clinical use.

                            Phase two is the transplantation of the stem cells. This is done in one of three ways:

                            1) Lumbar puncture – a procedure used where stem cells can be injected directly into the spinal column.

                            2) Intravenous injection- stem cells are injected into the patient’s vein.

                            3) Tissue injection – direct injection into target tissues.

                            Phase three involves the monitoring of the patient to make sure there are no adverse side effects. The only side effects reported to date were caused by the lumbar puncture, and not the stem cell treatment itself, with only 15% of patients reporting mild headaches. During the time under medical supervision, patients undergo various physiotherapy activities and other treatments as necessary.

                            Stem Cell Research and Treatment in China

                            ]]>

                            China is fast becoming a world leader in stem cell research, and is now a major centre for the stem cell treatment of many diseases and conditions. The Chinese government has poured many millions of dollars into research on regenerative medicine, and that investment has really borne fruit in the last few years. As a result of this expanded investment, Chinese contributions to scientific journals on regenerative medicine topics leapt from 37 in year 2000 to 1,116 in 2008, exceeded only by the contributions of experts in the USA, Germany, Japan and the UK.

                            read....

                            http://cell-division.magnesiumforhea...-new-frontier/

                            Comment


                            • This article makes it sound like it is happening all the time.

                              Comment


                              • Cholesterol-Lowering Drug May Help to Prevent Surgery-Related Spinal Cord Damage
                                Released: 8/23/2011 10:00 AM EDT
                                Source: International Anesthesia Research Society (IARS)

                                Could Statins Help to Reduce Paraplegia Risk after Aortic Surgery?

                                Newswise — San Francisco, CA. (August 22, 2011) – The cholesterol-lowering drug simvastatin appears to reduce spinal cord injury caused by oxygen deprivation in experimental animals, according to a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

                                With further research, treatment with statin drugs might provide a new approach to lowering the risk of paraplegia as a complication of surgery involving the aorta, the new research suggests. The experimental study was led by Takeshi Saito, Ph.D., of Nigata University Graduate School of Medical and Dental Sciences, Japan.

                                Simvastatin Reduces Spinal Cord Damage from Ischemia/Reperfusion Injury
                                The researchers used a standard technique to produce spinal cord damage due to oxygen deprivation in laboratory rats. This technique simulates a serious complication that can occur in patients undergoing major surgery involving the aorta, such as surgery to repair an aortic aneurysm. In this situation, temporary interruption of blood supply (ischemia/reperfusion injury) can lead to spinal cord injury and paraplegia.

                                In the experiments, rats received either simvastatin or an inactive treatment for one week before interruption of blood supply to the spinal cord, plus an additional dose 24 hours after blood flow was restored. Signs of spinal cord damage and paraplegia were compared between the two groups.



                                more...

                                http://www.newswise.com/articles/cho...al-cord-damage

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