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Spinal Cord Injury Articles Posted by Manouli

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    NEWS RELEASE 15-MAR-2021
    UofL, Medtronic to develop epidural stimulation algorithms for spinal cord injury
    $7.8 million from NIH will fund development of a closed-loop system to monitor and adjust for multiple functions, use wireless monitoring

    LOUISVILLE, Ky. - Researchers at the University of Louisville made news worldwide in 2018 when two people diagnosed with complete spinal cord injuries recovered the ability to walk thanks to experimental use of a therapy known as epidural stimulation. The news gave hope to people living with complete spinal cord injuries, a diagnosis that historically meant they were unlikely to regain function below their level of injury.


      One step closer to treating spinal cord injury with our own stem cells
      March 15th 2021
      Justin Varholick, PhD

      Recently, a team of scientists from Yale University and Sapparo Medical University in Japan treated spinal cord injury patients with their own bone marrow derived mesenchymal stem cells (MSCs), increasing their ability to walk and use their hands. Previous to the treatment, 13 patients had sustained falls or minor spinal trauma resulting in loss of motor function, coordination, sensory loss, as well as bowel and bladder dysfunction. After being bedridden for several weeks from an unexpected fall, the first patient was extremely thankful to be able to independently use a wheelchair and walk upright with a walker. Thanks to their own stem cells.

      NEWS RELEASE 11-MAY-2021
      Cell reprogramming could aid spinal cord injury recovery


      Cells called astrocytes normally support our neurons, and now scientists are working to reprogram the star-shaped cells into neurons that help reconnect the brain and body after a spinal cord injury.

      "We are at the stage of optimization. We know this reprogramming is feasible and we can do it," says Dr. Hedong Li, molecular neuroscientist in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia.

      Last edited by manouli; 24 May 2021, 4:15 PM.


        MARCH 23, 2021
        Nanobiomaterial boosts neuronal growth in mice with spinal cord injuries
        by Tongji Hospital of Tongji University

        Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine. The researchers were also able to identify the underlying genetic mechanism by which LDH works. This understanding should allow further modification of the therapy which, in combination with other elements, could finally produce a comprehensive, clinically applicable system for spinal cord injury relief in humans.



          I everybody! On April 10, I did the J&J Vaccine then, the next day saying about blood clot, lol. I feel good no problems! I am checking my self every day, but I am not worry everything is looking good. I wish all of you to be healthy! Soon, I'll post some new articles so we can see what's going on with the cure. I am getting older by the day, I want some good news for all of us! We have lost so many people and is so sad! xxxooo,manouli
          Last edited by manouli; 20 Apr 2021, 3:35 PM.


            God bless you Dear Manouli. Yes we need cure before we die


              Inflammatory response could hamper spinal cord injury

              Spinal Cord injury is a major condition in the United Sates. It is believed that an estimated 1.3 million people in the U.S are suffering from spinal cord injury, experiencing paralysis and difficulties that comprise of bladder, bowel and sexual dysfunction and persistent pain.
              A new research claims that an inflammatory response following a spinal cord injury seems to cause further tissue damage instead of encouraging healing. Researchers examining this inflammatory response in mice found that the kinds of cells enrolled to the location of the injury are apparently conquered within a week by those that endorse continue.....

              NEW ARTICLE 6/5/21
              Clinical Trial Could Help Paraplegics Walk Trial In Australia
              CANBERRA, Australia — Australians paralyzed by spinal injury could soon move and walk again, if an Australian clinical trial exploring a neurological treatment is successful.

              Led by researchers at Neuroscience Research Australia (NeuRA) the landmark international trial aims to restore the function of remaining spinal nerves through neurostimulation. Neuroscience Research Australia (NeuRA) is an independent, not-for-profit research institute based in Sydney, Australia. As a leader in brain and nervous system research, our goal is to prevent, treat and cure brain and nervous system diseases, disorders, and injuries through medical research.


              How to recover from a spinal cord injury
              The Hindu6 Jun 2021Aswathi Pacha The Hindu.

              Spotlight on recovery: A high-resolution image of the treated spinal cord.
              A violent fall, a vehicular accident, or a sports injury can sometimes damage the spinal cord and brain leading to paralysis and other lifethreatening health problems. The nerve fibres that carry important information are unable to regrow, leading to irreversible damage. Using novel bioinformatics frameworks and screening platforms, researchers have now identified a new gene combination that can help enhance the growth of nerve fibres after an injury.

              Last edited by manouli; 6 Jul 2021, 5:37 PM.


                New treatment targeting senescent cells boosts functional recovery from spinal cord injury
                James Ducker, MRes
                By James Ducker, MResJul 6 2021
                Reviewed by Emily Henderson, B.Sc.
                Senescent cells prevent tissue recovery following spinal cord injury, and a new drug targeting these cells could therefore improve functional recovery capacity.
                Exploring treatments for spinal cord injury in animal models
                Notorious for having a poor ability to recover from spinal cord injuries, mammals often suffer from whole-body paralysis following such recoveries. This contrasts to other taxonomic groups, such as fish, that can recover from injury relatively rapidly in comparison.