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Paraplegic move legs after stem cell procedure- Brazilian Center of Cell Theraphy

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    #61
    well. I am hoping. But there is an old saying. " we live in hope and die in despair. "




    Every area of trouble gives out a ray of hope; and the one unchangeable certainty is that nothing is certain or unchangeable.
    Han: "We are all ready to win, just as we are born knowing only life. It is defeat that you must learn to prepare for"

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      #62
      The status on this particular trial has changed from recruiting to active but not recruiting. They've evidentally had a huge amount of interest in this trial with 1,500 people but only room for 20 to start their Phase 1 safety. I hope everything continues to go well with it! unite2fightparalysis.org/clinicaltrials
      Last edited by GRAMMY; 27 Oct 2011, 6:00 PM.
      http://spinalcordresearchandadvocacy.wordpress.com/

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        #63
        Does anyone know if this type of therapy is thought to help non-traumatic spinal cord injuries such as spinal cord stoke? I am very confused on how current trials might help some like myself, so if anyone has any insight, I would love the hear it.
        Thanks.

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          #64
          Originally posted by Marcus View Post
          Interview with Dr Marcus Vinicius (video in the bottom of the page)

          http://g1.globo.com/bahia/noticia/20...aign=sharethis

          01) This phase involves 20 patients.
          02) So far 5 patients underwent the procedure.
          03) He expect that all 20 patients will be operated until the end of the first half of 2012.
          04) when talking about the rapid improvement of the patient, he says that animal tests already showed this. In animals the improvements occurred in 2 to 3 weeks.
          05) he says that other patients also had a rapid evolution.
          06) After completed this phase, they will be testing on a larger number of patients.
          07) the queue of people interested in participating in the study is something around 1500 people.
          08) in the first group operated there has been no problem. Patients left the hospital 48 hours after the procedure.
          09) Only after all 20 patients have been operate, they will be able to say that the technique is safe.
          10) Similar tests, but with other types of cells and different techniques, are being tested to treat strokes by another team at another hospital.
          11) he believes that these techniques under developing may be being used to treat patients in 5 or 10 years.
          12) all 5 patients treated so far showed some improvement, but in varying degrees. Some showed improvement in sensitivity, others in sfincters and motor abilities.
          13) they want to discover why a patient have better results than others.
          14) He finalizes alerting people to be patience and not to undergo unproven treatments.
          Marcus, thank you so much for this update. Keep the information coming, we are so very hopeful!

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            #65
            I understand their Phase 2 will have approximately 60 people if all goes well.
            http://spinalcordresearchandadvocacy.wordpress.com/

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              #66
              can anyone contact the guy and get him on here? call newspaper? get a message to him?
              Han: "We are all ready to win, just as we are born knowing only life. It is defeat that you must learn to prepare for"

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                #67
                If this therapy does something great in phase2 trial then within how much time we can get this treatment? I hope phase2 and phase3 do not take much time.

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                  #68
                  jhope, I will see if I can invite him to join us here.

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                    #69
                    Marcus good idea.

                    It looks foreigners may not be able to join phase2 trial at least because of huge interested patients. May be wait for phase3 or in case of success in phase2 then may be some one else do this same anywhere

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                      #70
                      Originally posted by Jawaid View Post
                      Marcus good idea.

                      It looks foreigners may not be able to join phase2 trial at least because of huge interested patients. May be wait for phase3 or in case of success in phase2 then may be some one else do this same anywhere
                      i was more hoping wise young could get involved and start some trials in china, usa, and others.

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                        #71
                        Barrington wise might not be taking foreigners in trials i guess because lot of money is needed. Brazil can take patients from other countries but they have already huge patients in Brazil. Only Stemcell Inc taking patients from other countries but criteria is very very tight.

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                          #72
                          Marcus still no protocol of the treatment been told by these researchers. I mean how they are treating and which hormones and proteins they have added in trial? When they will give details of the therapy?

                          May be some other country or doctor can do this therapy elsewhere as we could get soon.

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                            #73
                            With this news you can say that a new chapter has started in SCI.
                            Clinical trials and results.

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                              #74
                              KIM,

                              I would have to agree with your post #73.

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                                #75
                                Originally posted by Jawaid View Post
                                Marcus still no protocol of the treatment been told by these researchers. I mean how they are treating and which hormones and proteins they have added in trial? When they will give details of the therapy? May be some other country or doctor can do this therapy elsewhere as we could get soon.
                                Jawaid, I believe only the cells themselves are being injected and safety being evaluated in this Phase 1. The aim of this study is to evaluate autologous bone marrow stem cells transplantation as a safe and potentially beneficial treatment for patients with spinal cord injury.

                                The surgery will remove the scar tissue in the damaged area. With the free area, the application of stem cells will be done in the exact location of the trauma. According to Santos, the procedure should encourage the growth of injured nerves. At surgery, the patient will receive blood plasma rich in platelets. "This causes a clot structure that keeps stem cells in the lesion site."


                                They are however working with other cells types and growth factors for future trials in stroke models at the same hospital for consideration. This isn't currently a "combination" type of trial at this phase 1 with hormones and proteins being added. They're just testing safety of the cell injections alone. (Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury)

                                Estimated Primary Completion Date:January 2012 (Final data collection date for primary outcome measure)

                                Estimated Study Completion Date:January 2013

                                http://clinicaltrials.gov/ct2/show/NCT01325103?term=nct01325103&rank=1
                                Last edited by GRAMMY; 29 Oct 2011, 10:44 PM.
                                http://spinalcordresearchandadvocacy.wordpress.com/

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