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Breaking News: Paralyzed Man Stands, Moves With Epidural Stimulation

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  • Breaking News: Paralyzed Man Stands, Moves With Epidural Stimulation

    http://www.medpagetoday.com/Neurolog...eurology/26592,
    i havent read this yet, but when the did my last spinal cord stim surgery or one of the last ones, they tried a caudal entrance that had to be removed in the recovery room since it was touching my motor muscles. i already was able to use those muscles so it was not a breakthrough it was a failed attempt as it was useless to me
    i havent read this yet, just got the email.
    cauda equina

  • #2
    http://www.guardian.co.uk/world/2011...ry-rob-summers
    Paralysed baseball star steps into medical history
    Rob Summers was told he would never walk again after he was hit by a speeding car but was determined to prove doctors wrong


    Sarah Boseley, health editor
    The Guardian, Friday 20 May 2011
    Article history

    Rob Summers suspended on a treadmill, helping his legs relearn how to walk
    Baseball champion Rob Summers was hit by a speeding car in Portland, Oregon, three years ago, which smashed into his legs and left him with appalling injuries. He was told he would spend the rest of his life in a wheelchair at best. But the 25-year-old is now making history – as the first person paralysed from the chest down to stand and take a step unaided.

    The small and shaky movements that Summers has achieved spell real hope for all those who have suffered a spinal cord injury, and possibly even for those paralysed by other causes such as stroke.

    When he was in hospital, doctors told Summers he would never walk again, he said. "They said that I had no hope and to just give up. My comment was you don't know me very well. I'm going to fight until I get well again." To stand again and take steps, he said, "felt incredible. It was amazing. It made me optimistic and hopeful again for the future. I'm excited at being a part of this."

    Summers' legs are able to move because of electrical stimulation from a device implanted in his lower spine. Two hard years of training, suspended over a treadmill with physiotherapists manipulating his legs to stand and walk have helped build up the spinal cord neural network which processes signals to and from his legs.

    The real discovery has been that it is not the brain that is in charge of movement, but the legs and the spinal cord.

    His achievement is the culmination of many years of hard work and intense scientific endeavour funded by the Christopher and Dana Reeve Foundation, set up to try to find a way to restore movement to the former Superman star Christopher Reeve – who was paralysed in 1995 as the result of a riding accident – and others like him.

    Summers, a college baseball player for Oregon state who had helped his team win the college world series just six weeks before the hit and run driver wrecked his life, was exceptionally fit when he was injured.

    Although unable to move any part of his legs or feet, he has some residual feeling. This may mean that the astonishing progress made in his case may not be replicable in everybody. But there is now more than hope.

    "This is a breakthrough. It opens up a huge opportunity to improve the daily functioning of these individuals ... but we have a long road ahead," said Professor Susan Harkema from the Kentucky spinal cord research centre at the University of Louisville, one of two leading neurologists involved in Summers' treatment.

    Harkema describes the impulse from the brain to start walking as "facilitatory". What really starts the walking process, she says, is probably the shifting of weight to one foot.

    "The brain is not controlling movement to the extent we thought it was. If you think about walking, it sets up the nervous system to expect information related to walking," she said. That sensory information comes from the legs.

    This has been known and accepted in animals for some time, she added, but it was thought it might not be so in humans because of the highly developed brain.

    "The spinal cord is smart," said Harkema's chief collaborator, neurologist Professor V Reggie Edgerton from the David Geffen school of medicine at UCLA.

    "The neural networks in the lumbosacral spinal cord are capable of initiating full-weight bearing and relatively coordinated stepping without any input from the brain. This is possible, in part, due to information that is sent back from the legs directly to the spinal cord."

    The details of the neurologists' work with Summers are published in the Lancet medical journal.

    The results need to be replicated in other patients and the neurologists also hope to work with paralysed patients with other kinds of injury. But, said Susan Howley, executive vice president for research at the Reeve Foundation, it demonstrates proof of concept. "It's an exciting development. Where it leads from here is fundamentally a matter of time and money," she said.

    Other neuroscientists applauded the work in a commentary in the Lancet. Dr Grégoire Courtine and Dr Rubia van den Brand from Zurich University and Dr Pavel Musienko from St Petersburg wrote that they expected "this novel phenomenon of electrically enabled motor control" would inspire new thinking. They added: "We are entering a new era when the time has come for spinal-cord injured people to move."

    Meanwhile, Summers hopes to run and play baseball again one day. It has been, he acknowledged, "one great emotional rollercoaster with highs and lows. There were points of anger and frustration, but I would refocus on my goals." His family, he said, had been incredibly supportive.

    He hopes now to make a movie. "My goal is that through making a movie of my life story, I will help the millions of people around the world, paralysed and in wheelchairs, who have lost hope, and show them there is a brighter future ahead."

    Comment


    • #3
      I just read the article. Awesome!!!

      Comment


      • #4
        Should be on world news tonight.

        Comment


        • #5
          wow, they kept this pretty quiet. Very interesting concept with seemingly good results so far.

          Comment


          • #6
            http://abcnews.go.com/Health/paralyz...ry?id=13641521

            Comment


            • #7
              Good news.
              T5/6, ASIA A, injured 30 Nov 08
              Future SCI Alumnus.
              I don't want to dance in the rain, I want to soar above the storm.

              Comment


              • #8
                " the patient recovered supraspinal control of some leg movements, but only during epidural stimulation "

                this reminded me of 4-ap !!

                still good news

                Thanks

                Comment


                • #9
                  Sorry, I missed the bit where activation of the central pattern generator was going to get us out of the chair. The media are acting like it is a Cure. Let's concentrate on regeneration of the CNS please.

                  I have queues of colleagues coming up to my desk here in the UK to tell me all about this "wonderful news".

                  Comment


                  • #10
                    Yes FPF, i am living the same situation here…
                    ….everything is called cure but all these things are only palliative…..
                    Let's focus on regeneration of the CNS

                    Comment


                    • #11
                      I've just seen this on the news and I'm not sure what all the fuss is about. I think they're making a big story out of nothing. They've only achieved this on one very fit man, wow!, Why don't they start reporting news like this when they've done it on a few hundred people, this is just another case of getting people's hopes up for nothing.

                      I don't want these type of electrodes attached to me, I want to be able to feel my skin, walkaround normally, have control over my bodily functions, these electrodes don't give you any degree of independence back whatsoever.
                      Tetraplegic & Spinal Injury Site

                      Comment


                      • #12
                        I would say that I'm a pretty positive guy, but this news is not good news.
                        It will actually set back money for REAL regeneration work. Why pay more for a cure when we already got one? This will be the refrain.
                        I've had friends send me this article all day long and bless their souls, but they're being duped by a propaganda machine.
                        Are people reading the articles? This has not changed his daily life one iota. I'm happy for him because he feels positive, that's a good thing, but that's the end of the benefit.
                        When I interviewed Noela Valis from the New Zealand Spinal Cord Society she told me that when she got involved in the game 25 years ago they were doing this with dogs at Purdue. 25 years later we're doing this with humans, that is not progress.
                        We are in 2011 and have real evidence of regeneration in animal models and loads of clinical trials have started, so why are we still looking at this kind of electrode model as some sort of cure.

                        If Aretha Franklin sang it she would demand R-E-G-E-N-E-R-A-T-I-O-N. She's old news too, but at least she's not passe.
                        Dennis Tesolat
                        www.StemCellsandAtomBombs.blogspot.com

                        "Change does not roll in on the wheels of inevitability, but comes through continuous struggle. And so we must straighten our backs and work for our freedom."
                        Martin Luther King

                        Comment


                        • #13
                          StemCells, totally agree with you. An inovation yes, cure no. We're looking ahead for a cure.

                          keeping on

                          Comment


                          • #14
                            Maybe this approach combined w/ stem cells and intensive therapy for another group in clinical trials, might be a good idea.
                            Donnie: Dr. Xiao, What are your thoughts on a cure/combination therapy for SCI's??
                            CG Xiao: Donnie, I don't want to disappoint you, but I think it is impossible to restore the continuity of the cord or "bridge the gap" in the near future, let's say: 50 years. Dr Wise Young has been my most respected scientist in SCI. He has dedicated and contributed to SCI no other can match.

                            Comment


                            • #15
                              Originally posted by StemCells&AtomBombs View Post
                              I would say that I'm a pretty positive guy, but this news is not good news.
                              It will actually set back money for REAL regeneration work. Why pay more for a cure when we already got one? This will be the refrain.
                              I've had friends send me this article all day long and bless their souls, but they're being duped by a propaganda machine.
                              Are people reading the articles? This has not changed his daily life one iota. I'm happy for him because he feels positive, that's a good thing, but that's the end of the benefit.
                              When I interviewed Noela Valis from the New Zealand Spinal Cord Society she told me that when she got involved in the game 25 years ago they were doing this with dogs at Purdue. 25 years later we're doing this with humans, that is not progress.
                              We are in 2011 and have real evidence of regeneration in animal models and loads of clinical trials have started, so why are we still looking at this kind of electrode model as some sort of cure.

                              If Aretha Franklin sang it she would demand R-E-G-E-N-E-R-A-T-I-O-N. She's old news too, but at least she's not passe.
                              Sorry, forgot the link http://www.youtube.com/watch?v=z0XAI-PFQcA
                              Dennis Tesolat
                              www.StemCellsandAtomBombs.blogspot.com

                              "Change does not roll in on the wheels of inevitability, but comes through continuous struggle. And so we must straighten our backs and work for our freedom."
                              Martin Luther King

                              Comment

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