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    This group is not associated with ChinaSCINet.

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      Jim, do you know when we can expect wise to be able to come online and give us an update ? He must be working very hard to be AWOL for so long
      "That's not smog! It's SMUG!! " - randy marsh, southpark

      "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


      2010 SCINet Clinical Trial Support Squad Member
      Please join me and donate a dollar a day at http://justadollarplease.org and copy and paste this message to the bottom of your signature

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        H will be in tomorrow, I'll ask.

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          Dear Professor Wise,

          In this recent article (http://medicalxpress.com/news/2014-0...yzed-rats.html) , summing up a publication from Science, researchers from Zurich (including Pr. Schwab that was so far pursuing clinical trials testing Nogo inhibition) seem to consider that “Only if the timing, dosage and kind of rehabilitation are right can motor functions make an almost full recovery after a large stroke.”



          In your trials, do you also consider “timing” and “sequence” as such important issues ?

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            Originally posted by spinedoctor View Post
            Dear Professor Wise,

            In this recent article (http://medicalxpress.com/news/2014-0...yzed-rats.html) , summing up a publication from Science, researchers from Zurich (including Pr. Schwab that was so far pursuing clinical trials testing Nogo inhibition) seem to consider that ?Only if the timing, dosage and kind of rehabilitation are right can motor functions make an almost full recovery after a large stroke.?



            In your trials, do you also consider ?timing? and ?sequence? as such important issues ?
            Yes, I believe that appropriate rehabilitation of sufficient intensity and duration is essential for recovery of motor function in clinical trials.

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              Originally posted by lunasicc42 View Post
              Jim, do you know when we can expect wise to be able to come online and give us an update ? He must be working very hard to be AWOL for so long
              Was on here but didnt answer to that, hopefully no news is GOOD news

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                Originally posted by allenstevens View Post
                Was on here but didnt answer to that, hopefully no news is GOOD news
                Yes ,but the wait is excruciating
                "That's not smog! It's SMUG!! " - randy marsh, southpark

                "what???? , you don't 'all' wear a poop sac?.... DAMNIT BONNIE, YOU LIED TO ME ABOUT THE POOP SAC!!!! "


                2010 SCINet Clinical Trial Support Squad Member
                Please join me and donate a dollar a day at http://justadollarplease.org and copy and paste this message to the bottom of your signature

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                  If I have seemed AWOL over the past few months, it is mostly because I have been very busy analyzing data, writing papers, raising funds, and organizing phase III trials of umbilical cord blood mononuclear cells and lithium treatment of chronic spinal cord injury in multiple countries. In the meantime, we are continuing clinical trials of umbilical cord blood mononuclear cell therapy of subacute spinal cord injury (https://clinicaltrials.gov/ct2/show/...ic+pain&rank=1) and chronic stroke (http://clinicaltrials.gov/ct2/show/N...+stroke&rank=3), and lithium treatment of neuropathic pain in spinal cord injury (https://clinicaltrials.gov/ct2/show/...ic+pain&rank=1).

                  The news is good in that all the findings that I have talked about to date seem to be confirmed by further detailed analyses of the data. We are also gaining new insights into the mechanisms of recovery and this is helping us design the upcoming clinical trial. Finally, we are hoping that the papers will be accepted and published.

                  Wise.

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                    Wise does this mean that you are planning another Phase and this won't be made available to SCI in 2015?

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                      I believe he's trying to make the phase 3 trial available by the end of 2014, at least he and Jim have said that multiple times.

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                        Let me rephrase that

                        Originally posted by JamesMcM View Post
                        I believe he's trying to make the phase 3 trial available by the end of 2014, at least he and Jim have said that multiple times.

                        I thought Phase III was started in 2013- I guess what I was asking is I have read if this Phase were to go good Professor Wise was going to pursue to push it out to be made available to SCI with trying for a "compassionate use".. I thought after this third Phase was completed that it would be proven?

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                          Dr Young.
                          I remember you saying that you wanted to use the bioness for hand function this upcoming trial. Did you ever get that strait or did you decide not to use it? Also I guess your using that because its harder to retrain fine motor than your walking gait. Are you going to incorporate the locomat into your next phase also?

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                            Will these patients be re-evaluated after 2 years from treatment?

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                              Can someone remind me, what was the date of the final patients treatment?

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                                Is this something new that hasn't been talked about on these forums yet?

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