I don't think you guys read the paper and understand the results of the trial. The attached graph shows the changes that occurred in the 20 patients that participated in the Kunming/6-6-6 Trial.
Left Column, go down to Age (age at time of trial), next is Years (years after injury), HLA (match of umbilical cord blood injected), AIS (ASIA Score before and after), KLS (Kunming Locomoter stages), WISCI (Walking Index of Spinal Cord Injury), Motor (Motor Scores), Touch, PIN (pinprick), MAS (Modified Ashworth Scale for Spasticity, VAS (Visual Analog Scale (level of pain), SCIM (Spinal Cord Independence Measure), SAE (Severe Adverse Events (Codes listed on right of graph).
Look at AIS (ASIA Score) row- injured 6 years, improved from A to B. Injured 20 years, improved from A to C. Injured 14 years, improved from A to C. Injured 3 years, improved A to B.
The real story is in the improvements of the Spinal Cord Independence Measures (SCIM). Every patient except one improved pretty dramatically here, and this is where it counts. This therapy gave independence back, the ability to do things on their own. The paper is more specific and you should read the details.
The Phase IIb Trial has been refined and will likely be more effective. Of course 6-6-6 is difficult but we will find more efficient ways. We aren't going to discover a near cure in the beginning trials but we have to start somewhere. Regaining independence is where we start.
Left Column, go down to Age (age at time of trial), next is Years (years after injury), HLA (match of umbilical cord blood injected), AIS (ASIA Score before and after), KLS (Kunming Locomoter stages), WISCI (Walking Index of Spinal Cord Injury), Motor (Motor Scores), Touch, PIN (pinprick), MAS (Modified Ashworth Scale for Spasticity, VAS (Visual Analog Scale (level of pain), SCIM (Spinal Cord Independence Measure), SAE (Severe Adverse Events (Codes listed on right of graph).
Look at AIS (ASIA Score) row- injured 6 years, improved from A to B. Injured 20 years, improved from A to C. Injured 14 years, improved from A to C. Injured 3 years, improved A to B.
The real story is in the improvements of the Spinal Cord Independence Measures (SCIM). Every patient except one improved pretty dramatically here, and this is where it counts. This therapy gave independence back, the ability to do things on their own. The paper is more specific and you should read the details.
The Phase IIb Trial has been refined and will likely be more effective. Of course 6-6-6 is difficult but we will find more efficient ways. We aren't going to discover a near cure in the beginning trials but we have to start somewhere. Regaining independence is where we start.
Comment