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  • Nose cells help spinal injury healing

    Nose cells help spinal injury healing

    http://www.sciencealert.com.au/news/...1-18501-2.html

    Cells from the human nose are showing further promise in remediating spinal cord injury, according to research from the University of New South Wales (UNSW).

    Six weeks after injecting cells from the human nose (olfactory ensheathing glia) into the injured spinal cords of rats, the researchers found improvements in the animals' movement.

    "We found improvements in hind limb function of these animals," said Dr Catherine Gorrie, from the Neural Injury Research Unit at UNSW. "They performed significantly better on locomotive tasks than those who didn't have the injections."

    This is the first time that cells from the human nose have been used on rats with such injuries, which is an important step towards future clinical trials in humans.

    The work has just been presented at the Society for Neuroscience Conference in Washington, DC.

    Spinal cord injury affects about 12 000 Australians and there are 300-400 new cases each year, according to StepAhead Australia.

    "One of the real positives about using these cells is that they are very accessible," said Dr Gorrie, who is based in the School of Medical Sciences. "It's a relatively simple procedure to take them from the patient and grow more of them and then insert them back into the same person. This reduces the risk of rejection."

    Olfactory ensheathing glia are a special type of cell that normally help to guide new nerve fibres from the lining of the nose into the brain throughout life. These cells have unique properties that may be used to guide new spinal cord nerve fibres after injury.

    Previous work from the Neural Injury Research Unit shows that a delayed transplantation of cells is more effective than injections given at the time of injury. In this case, the animals were given the cells a week after the injury.

    "We think these cells have a lot of potential," said Dr Gorrie. "What we want to do now is determine what makes these cells effective."

    The National Adult Stem Cell Research Centre, Griffith University (QLD) was a collaborator, preparing the cells for the project.
    "I QUESS THEY'LL HAVE TO RUN OUT OF RATS, BEFORE THEY TRY IT OUT IN HUMANS. WAKE ME UP WHEN IT'S OVER !!!"

  • #2
    am i wrong in thinking this has been done quite a while ago

    this statement must have been a reporters conclusion,

    This is the first time that cells from the human nose have been used on rats with such injuries, which is an important step towards future clinical trials in humans.

    pleaseeee correct me if i am wrong
    http://justadollarplease.org/

    2010 SCINet Clinical Trial Support Squad Member

    "You kids and your cures, why back when I was injured they gave us a wheelchair and that's the way it was and we liked it!" Grumpy Old Man

    .."i used to be able to goof around so much because i knew Superman had my back. now all i've got is his example -- and that's gonna have to be enough."

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    • #3
      Interesting article.
      I have to ask if anyone has seen the Woody Allen movie, SLEEPER, where there is an amazingly funny scene where they attempt to 'clone' the leader from his nose. Woody and Diane Keaton are running around holding a nose and repeating , "We must clone the nose !"

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