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Baclofen vs. Dantrolene??

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  • Baclofen vs. Dantrolene??

    I have been prescribed both baclofen and dantrolene for muscle spasms and was wondering what the difference was?

    Normally, I take a 20mg pill of baclofen 4x a day, and a 10mg pill of Dantrolene 2x a day.

    Reason I ask is because yesterday Walgreens couldn't fulfill my prescription.. I guess Medicare rolled me over into a new plan on Jan. 1, and the information was not available or updated when the pharmacist called them.

    So I haven't taken any baclofen for 24 hours, and wasn't able to sleep last night. I have been taking a lot more Dantrolene pills to make up for it, mostly when I feel spasms. But I still feel like a crackhead, all twitching and shit and it feels like I have electricity running through my veins!


    Is there like an equilizer or something? Like 10 Dantrolene = 1 baclofen? Some kinda chart? A scale? Is this safe? F Medicare, they wont pay for my new wc either

  • #2
    I was told by my Doc, YMMV, that cold turkey on Baclofen was a big no-no. Your Part D doesn't cover Baclofen any longer?!?! I hope that doesn't happen to me. I just started Medicrap this year. Who is your Part D provider? I use Wellcare (the Walgreens owned insurance company) and Baclofen is on their formulary.
    "I have great faith in fools; self-confidence my friends call it." - Edgar Allen Poe

    "If you only know your side of an issue, you know nothing." -John Stuart Mill, On Liberty

    "Even what those with the greatest reputation for knowing it all claim to understand and defend are but opinions..." -Heraclitus, Fragments

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    • #3
      MattGimpin,

      You should be posting this to the Care Forum (not in the Science and Technology Forum). I am moving this to that forum where you should get attention and answers to your question.

      I doubt very much that insurance will no longer cover baclofen. There is a misunderstanding. Dantrolene is an older anti-spasticity drug that has not been used as much for a long time.

      In my opinion, Dantrolene is not a good substitute for baclofen. It works by a different mechanism and has more side-effects. You need to get your prescription for bacloften refilled. If baclofen alone does not work, the general approach is to add another anti-spasticity drug such as tizanidine.

      The dose of oral baclofen is 40-120 mg per day. The dose of dantrolene is 25-400 mg/day.

      Wise.

      Originally posted by MattGimpin View Post
      I have been prescribed both baclofen and dantrolene for muscle spasms and was wondering what the difference was?

      Normally, I take a 20mg pill of baclofen 4x a day, and a 10mg pill of Dantrolene 2x a day.

      Reason I ask is because yesterday Walgreens couldn't fulfill my prescription.. I guess Medicare rolled me over into a new plan on Jan. 1, and the information was not available or updated when the pharmacist called them.

      So I haven't taken any baclofen for 24 hours, and wasn't able to sleep last night. I have been taking a lot more Dantrolene pills to make up for it, mostly when I feel spasms. But I still feel like a crackhead, all twitching and shit and it feels like I have electricity running through my veins!


      Is there like an equilizer or something? Like 10 Dantrolene = 1 baclofen? Some kinda chart? A scale? Is this safe? F Medicare, they wont pay for my new wc either

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      • #4
        Hi Matt,

        I agree that you should not stop BAclofen cold turkey and taking Dantrolene is not a substitute for Baclofen. As Wise pointed out, they work by different mechanisms.
        The recommended max dose of baclofen is 80mg which is what you are taking, so I can see why you were having the symptoms you were. I would re-contact your pharmacy or if needed have your doctors office call them. You shuold not be without this medication.

        AAD
        The SCI-Nurses are advanced practice nurses specializing in SCI/D care. They are available to answer questions, provide education, and make suggestions which you should always discuss with your physician/primary health care provider before implementing. Medical diagnosis is not provided, nor do the SCI-Nurses provide nursing or medical care through their responses on the CareCure forums.

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