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Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies.

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  • Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies.

    Int J Hematol Oncol Stem Cell Res. 2013;7(1):15-33.

    Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies.

    Ardeshiry Lajimi A1, Hagh MF2, Saki N3, Mortaz E4, Soleimani M5, Rahim F6.


    Author information


    Abstract

    Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. The recent advances in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.


    Free Full Text http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913133/
    http://www.ncbi.nlm.nih.gov/pubmed/24505515
    “As the cast of villains in SCI is vast and collaborative, so too must be the chorus of hero's that rise to meet them” Ramer et al 2005
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