BHT/BHA is used as preservative in chewing Gum, Cereals, Vegetable Oils(also used in hostels/ Government food programes, Free prasadams in Pilgirimage places or Chips which may be responsible for some disease condition which occur. Who knows the inclusion of bht & bha used as preservative in Chewing gums, cereals, vegetable oils or chips may be responsible for some disease condition which occurs to some humans not due to hereditary, since no immediate effect is not known immediately. But clearly exhibits the bad effect on animals immediately.
Effect of Amber polyherbal formulation was evaluated in butylated hydroxytoluene (BHT) induced toxicity of lungs and liver in rats. Toxicity was produced by administering BHT (500 mg/kg/day) for 3 days. Lung damage was evidenced by elevated levels of broncho alveolar lavage fluid (BAL) parameters such as protein, lactate, lactate dehydrogenase (LDH), alkaline phosphatase (ALP), acid phosphatase (ACP) and glucose-6-phosphate dehydrogenase (G6PDH). Liver damage was proved by elevated levels of serum protein and markers such as LDH, ALP, aspartate amino transferase (AST), alanine amino transferase (ALT), decreased level of lipid peroxides (LPO) in serum and glutathione (GSH) in liver.
Administration of aqueous suspension of Amber poly formulation (50 mg/kg orally) retained these elevated levels of BAL-protein, lactate, LDH, ALP, ACP, G6PDH and serum-protein, LDH, ALP, AST and ALT at near normal values. Decreased level of liver GSH was retained at near normalcy in Amber poly formulation pretreated BHT-administered animals. There was no change in liver LPO in all the four groups.
Amber Poly formulation is one of the rare formulation, which when treated does not affect the damage caused by bht or bha.
Amber poly formulation is the product for every human being who consume BHT / BHA enhanced products for a health life . Capsules targeted for this segment will be a boon to FMCG / FMHG companies to generate huge revenues. This May be a product required for every Indian to have a better quality of life.
Even the manufactures of oils, cereals, packaged ready to eat food , Chewing gums can use Amber poly formulation base to enrich there marketing value of there product and provide safety from included BHT / BHA.